??GPT???????????????????

1
???????????????

• ???????????
• 2009-08-24
• ???????

2
???????28???????????????????????????????

• ?? ????(NOEL)??????(EL)??????.
• ??????? ??? NOEL
• ????????????????????? ????????
• ?????????
• ??????????????? ??????
• ???????????

3
?????????

1. ???????109?28??????????/?????????
2. ???? ??????? (FOB)???????????????????????????????
   /??28??????
3. ??? ????????4???5?(37??)?1??????,5??????????,3???
   ???????????,???????????????

4
????????????

• Bartlett??????
• ????(???OK ??????)
• Dunnett???????,Scheffé???????,Duncan???????
• 3. Kruskal-Wallis???(???? ????? ??????????)
• Dunnett????????????,Scheffé????????????,Steel????
  ?????

5
???(Plt0.05)??????????(??1,????????)
???? ??? ?????????() ?????????() ?????????() ?????????()
???? ??? ??? ??? ??? ????
1 120 0 (0.0) 2 (1.7) 4 (3.3) 10 (11)
2 104 6 (5.7) 5 (4.8) 4 (3.8) -
108 130 2 (1.5) 4 (3.0) 16 (12) 31 (23)
109 116 1 (0.8) 1 (0.8) 2 (1.7) 9 (7.7)
??? 109 109 109 109 37
? ? 12167 205 414 1318 731/4074
??? 111 1.6 3.4 10 17
??? 162 8.4 17 36 55
??? 54 0.0 0.0 0.0 0.0
??? - 0.0 - - -
6
???(Plt0.05)??????????(??2, ?????????)
???? ??? ?????????() ?????????() ?????????() ?????????()
???? ??? ??? ??? ??? ????
FOB 68 1 (1.4) 3 (4.4) 8 (11) 1/10 (10)
??? 392 13 (3.3) 30 (7.6) 81 (20) 40/96 (40)
????? 3586 56 (1.5) 106 (2.9) 318 (8.8) 176/1198 (14)
????? 4285 79 (1.8) 163 (3.8) 455 (10) 267/1426 (18)
???? 1928 22 (1.1) 44 (2.2) 188 (14) 103/672 (15)
????/BW? 1908 34 (1.7) 68 (3.5) 268 (14) 144/672 (17)
?? 12167 205(1.6) 414 (3.4) 1318(10) 731/4074 (17)
7
???

1. ????????????26, 52, 78???104?????????????????????
   ?????,??????????????.??????????,??????????????????
   ?.
2. ????????????????????????? (NOAEL)?,???????????????
   ????.
3. ?????????,??????,?????????????12
   (lt5)????????NOAEL??????.