??B - PowerPoint PPT Presentation

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??B

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Title: Author: Masaru Wada Last modified by: MasaruWada Created Date: 11/12/1997 5:26:32 AM Document presentation format – PowerPoint PPT presentation

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Title: ??B


1
??B ??????
?7? ???????????
?? ?
???????????
2
?????????(????)
??(catabolism)
??(metabolism)
??(anabolism)
????????????????? ???
???????????????? ??????????
3
????
??A
??B
??C
??A
??B
??C
????????????(metabolic pathway)????
4
????? ???
??????TCA??????????????????
5
???????????
?????
????????or????
????CoA
6
??????????
??????????????????????????????????
???????????????????????
??????????????????????????????
7
????????
????????????????????????
8
????????
?????????????
6
5
1
4
2
3
???50???
9
??????
???????
?????????
10
?????????
???11061107 (?????6,00060,000) ?????????
????
????????100g?????????????600kcal????????????
???????????
11
????(??????)
?????(??) ???? 5105 2106 (?????
3,00012,000) ????????? ??
???????(????) ???? 1510640106
(?????90,000 250,000) ????????? ???
12
????
?????
???????
13
?????????
???????????
?????????????????????
14
????????????
?????????????????????????????????????????????
???????????????????????????
???????????????????????????????????
15
?????
???????????????????????????????????????????
E
E

16
?????????
??????????????-3-???????????????????
????????????(????????)?
17
?????????
?????????3-???
?? ??
18
??????
????CoA???????????????????????ß-??????????-CoA????
?????
CH3CH2CH2CH2----CH2COO-
CH3CH2CH2CH2----CH2CO-CoA
19
??????
CH3CH2CH2CH2----CH2CH2CO-CoA
FAD
FADH2
NAD
NADHH
20
??????
??????
TCA???
????-CoA
21
??????
????CoA????????1???????????2????????CoA???????????
?????ß-??????
22
??????(C18?????)
C18???????-CoA?9???? (ß-?????????8?)
???????CoA?? -2 ATP 9 ????-CoA ? 9 12 108
ATP 8 FADH2 ? 8 2 16 ATP 8 NADH2 ? 8
3 24 ATP ?? 146 ATP
23
??????????????
C17H35COOH 26O2 146Pi 146ADP ? 18CO2
164H2O 146ATP
C6H12O6 6O2 38Pi 38ADP ? 6CO2 6H2O
38ATP ?????????????????ATP??????????????????????
????????????????????
24
????????????
?????????????2????????CoA?????????????????3??????C
oA????
?????CoA
?????CoA
?
?
?
?
TCA???
25
???????
???????????????????????????????
??????????????????????????????????????????????????
?
26
???????
?????????????????????????(??????)
????
a-???
a-?? ?????
??????
27
???????
????????????????????????????????????
??????
a-???????
H2O NAD
????? NADHH
28
????????
?????????????????????????????????
??????????
??
?????
(????)
29
????
???2????????????
30
???????????
???????????????
1) TCA??????????? ATP???
2) ??????????????? (???????)
3) ????????????? (????????)
31
??????????
???????????????????NAD ???????????????
????????????????????????
??????????????????????????????????
32
?????????
????????????
???????????
33
??? ????
NADH ?? NAD??????
34
???
???????????????????
??????????????
35
???
?????6-???
?????
ATP
???????
????????????????????????????????????????????????
36
???
?????6-???
?????
Pi
H2O
?????-6-??????????
?????????????????????????????????
37
???
?????? -1,6-????
?????? -6-???
H2O
Pi
??????-1,6-???????????
??????-1,6-??????????????????????????
38
???
????????????
?????
ADP
ATP
??????????????
???? ??
????????????
?????
ATPCO2
ADP
GTP
GDPCO2
39
???????????????
????????100g?????????????600kcal????????????
?????????????????????????????????????
????????????????????????????????????
40
???? ? ??? ???
41
???????????
???????????????????????????????????????????????
???????????????????
???????????????????????????????????
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