Title: ???????? ????? ??????? E0
1????????
???? X ???? ????? ??? ??? ?? ??????? ???????
????? ????.
????
?????
2???????? ????? ??????? E0
- ???? ??? ????? ??? ?? ???? ?????? ???? ???? ???.
- ??? ???? ??? ?????? ?? ?? ????
- ???? ????? ?? ????? ???? ??? E0 ?????
- ???? ?????? ?? ????? ???? ??? E0 ?????.
3?????? ???????? ??????? ??? ???????
- H ???? ??????? ?- -X, ????? ????? ????.
????? ???? ????? ?-H2 - X ???? ??????? ?-H2 ????? ????? ????, ??????
????? ?- -X
4??? ??????? ?????? ?????????
5???? ???????? ?? ???????? ?????
6???? 2
??? ??
E0
DE0 -0.19 0.32V 0.13V
7??????? ??????? ?? ???? DG0
- ???? ????? ??? ??????? ??? ????????.
- ???? ????? ??????? ????????? ??????
DG0 -nF DE0
F23.06 kcal/V mol
8???? 3 ????? ????? 2 ????? ?? DG0
DE0 -0.19 0.32V 0.13V
9DG0 -nFDE0-2 x 23.06 x 0.13 -6 kCal/mol
??????? ????????
10???? ?????? ?????? ?????????? ?? ??????? ???????
11????? 4
?. ??? ?????? ???? ????? ???????? ?
DGO -7.3 10.3 3kCal/mol
12???? ??? ??? ???? ????? Creatine-P?
??? ??????? ???????
R1.98 cal/mol x ok T298oK
DG DG0 RTln
????? ?????? ??????? ????? ?? ?????? ?????????
??????-???? DG0, ????? ???? ?? Keq
13????? 5
?. ???
?DGO
14?. ???? ?? ???? ??? ATP ? ADP ??? 10. ?? ???? ???
?????? ???????????????? ?
3.27 x 104
15Energy Charge
- ???? ?? ?????? ??????? ?? ???.
?? ???? ??????? ????
ATP8OmM ADP8mM AMP9mM
0.78
16????? ????????
- ???? ??????? ??? ???? ?-DG0 ?? ??? ????????, ???
???? ?? ???? "?????????".
???????? ??? ?? ???? ????????
17????? 3
PPi