Lab This Week: EKGs and Blood Pressure

1
Lab This Week EKGs and Blood Pressure

• Bring textbook
• Bring calculator
• Wear clothes and shoes for running stairs
• Easy access to wrist and ankles for ECG
  electrodes
• Easy access to arms for Blood Pressure
  measurement
• Wear Wofford logo if you wanna be in Olencki pics

2
Revising Abstracts
Instructions forthcoming. Due date to be
announced. Keep all papers together for
resubmission!
3
For Friday Quiz

• Be prepared to draw and label electrocardiograms
  for
• Normal
• 1st degree heart block
• 2nd degree heart block
• Be able to diagnose from an ECG
• Atrial fibrillation
• Ventricular fibrillation
• Premature ventricular systole
• 3rd degree heart block

4
1QQ26 for 1030

1. Catecholamines acting on beta-adrenergic
   receptors cause arteriolar smooth muscles to
   relax.
2. Vasopressin is a vasoconstrictor.
3. Of the several modes of exchange in capillaries,
   diffusion is the most important for the delivery
   of nutrients and removal of wastes.
4. There are five Starling forces.
5. For bulk flow, water and colloids move through
   aqueous channels and intracellular clefts.

e) Was not graded. I intended the term to be
intercellular clefts and I didnt do a good job
of making a distinction.
5
1QQ26 for 1130

1. Catecholamines acting on alpha-adrenergic
   receptors cause arteriolar smooth muscles to
   relax.
2. Endothelin-1 is a vasoconstrictor.
3. Of the several modes of exchange in capillaries,
   bulk flow is the most important for the delivery
   of nutrients and removal of wastes.
4. There are only three Starling forces.
5. During bulk flow in capillaries, water and
   crystalloids move through aqueous channels and
   intracellular clefts.

e) Was not graded. I intended the term to be
intercellular clefts and I didnt do a good job
of making a distinction.
6
Figure 12.42
Bulk Flow through aqueous channels and
intracellular clefts
S 10
Starling Forces
Regulated by arterioles
Net filtration 4L/day
Main difference in the Pulmonary circuit?
7
Bulk Flow and Starling Forces
8
Who Cares?
S 12
Aunt Esther
Cancer of the liver Failure of hepatocytes to
produce plasma colloids
9
Aunt Ester
Pc
?c
10
Hypotension
Actions of Histamine and antihistamines
11
Fig. 12.43
S 11
Pc
Pc
Pc
12
Figure 12.41
S 13
Colloids
Crystalloids
Bulk Flow
13
Figure 12.47
S 1
Fate of 4 L/d excess filtrate
Liver Bone Marrow Spleen
Mode of propulsion?
14
Filariasis in Haiti Washington Post Article
15
Figure 12.44
S 2
Veins areCapacitance vessels(high
compliance)with valves for unidirectional flow
Arteries are low compliance, so any increase in
volume increases pressure.
16
Fig. 12.53
S 3
MAP CO x TPR
Negative feedback controlstimulus, receptors,
afferent pathway(s), integrator, efferent
pathway(s), effector(s)response(s)
17
Fig. 12.54
S 4
What happens to the set point for MAP during
exercise?
18
Story Time
S 5
A Neuroscientist in New Orleans
19
MAP CO x TPR
S 2

• Mean Arterial Pressure Cardiac Output x Total
  Peripheral Resistance

MAP (HR x SV) x TPR
Loss of 1 liter of blood from vein ? ? blood
volume ? ? MAP ? ..
Creating your Hemorrhage Diagram
20
  Beginning with a loss of about 1 liter of blood
from a vein, diagram the early events associated
with hemorrhage and the negative feedback
responses to hemorrhage in a well-organized
diagram. Write legibly! Completeness, accuracy,
and detail, together with the proper sequence
earn maximal points.   The following
abbreviations can be used AI, AII, JGA, mAChR,
Hct, Q, SV, EF, RBC, HR, EDV, ACh, ANH, ADH, CO,
TPR, EPO, VR, MAP, EPI, NE, SAN, aAdR , bAdR,
Symp (sympathetic), Parasymp (parasympathetic),
PV, r (radius), Pc, fAP (frequency of action
potentials.) Any other abbreviations must be
defined. "If in doubt, write it out!" Use
single headed arrows (?) to indicate sequential
relationships and doubled-stemmed arrows to
indicate increases or decreases.