Microslots and Microfluidic Logic

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Microslots and Microfluidic Logic

• Yael Maguire and Manu Prakash
• Oct 12, 2006

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If we make life...

• how will we understand what weve made?

Sweedler et al, Chem Rev, 1999
, Sweedler/Whitesides et al, APL, 1997
Massin et al, JMR, 2003
Walton et al, AnalChem, 2003

• 1013-1014 (100pmols -1nmol) biomolecules

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160 um
plug
8x more sensitive than best planar probe
1014 molecules
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Future
1010 molecules at room temperature
100 sensors in 5mm2
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Complexity in fluid manipulation
2005 2006 2007
1960s
Moores Law for Microfluidics
Increasing Complexity
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Microfluidic Bubble Logic
Nonlinearity
Bistability
Cascadability Feedback