Michael Bowdery

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Michael Bowdery

• Interim Head of NISCHR

Capacity Building and Opportunities for Capacity
Building in CTUs in Wales UKCRC CTU Directors
Meeting 13 November 2012
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Content

• Purpose
• To introduce you to some of the ways in which
  NISCHR supports capacity building in Welsh
  Clinical Trials Units
• Content
• Strategic context
• NISCHR Trials Units
• Capacity building in Welsh Trials Units

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NISCHR Strategy

• Supporting excellence and innovation
• Investing in the future (capacity building)
• Streamlining the research process and improving
  the research environment
• Increasing collaboration within and across
  sectors HEI, NHS and commercial

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NISCHR Trials Units

• 5 UKCRC Registered Trials Units in Wales
• 3 are NISCHR funded for Trials Unit activity
• 8.6m investment over 5 years
• Combined portfolio worth c105m (as at March
  2012)
• Funded to work on an all-Wales basis and beyond
• Units have complementary specialisms
• All have a remit for core activity involving
• development of new trials
• delivering funded trials
• methodological development
• unit management and strategic development
• Two NHS Research Design and Conduct Services
• Collaborating with 17 RRGs and Health Economists

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NISCHR Trials Units

• South East Wales Trials Unit (SEWTU)
• Led by Professor Kerry Hood, Cardiff
• SEWTU themes Infections, Behaviour Change,
• Children Young People, Medical Devices
• Noted strength in working across Primary Care
• North Wales Organisation for Randomised Trials in
  Health (NWORTH)
• Led by Professor Bob Woods, Bangor
• Focus on pragmatic trials, complex
  interventions, social care and SOP
  development
• Developing expertise in Ageing and Dementia,
  Mental Health, Muscular-Skeletal trials

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NISCHR Trials Units

• West Wales Organisation for Rigorous Trials in
  Health and Social Care (WWORTH)
• Led by Professor Ian Russell, Swansea
• Focus on Secondary Care trials
• Noted interest in Emergency Care,
  Gastroenterology, Diabetes, Mental Health,
  Rheumatology trials
• involving and exploring the use of routine
  data

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Other Trials Units

• Wales Cancer Trials Unit (WCTU)
• Led by Gareth Griffiths, Cardiff
• Core-funding from CRUK and Marie Curie
• Cancer focus (cancer therapies, primary care
  and palliative care) but non-cancer elements
  emerging
• Haematology Trials Unit
• Led by Dr Robert Hills, Cardiff
• Funding from CRUK, MRC, Leukaemia Lymphoma
• Research Fund (and others)
• Lead centre for acute myeloid leukaemia trials
  in the UK

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NISCHR Clinical Research Infrastructure
NISCHR Trials Units
NISCHR Infrastructure Support Groups
NISCHR Clinical Research Centre
NISCHR Registered Research Groups
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Impact of core funding on capacity building (1)

• Staff retention and development
• Bridging funding between projects
• Staff stability
• Funding shortfalls within projects
• Academic development areas outside the focused
  funded projects critical for academic
  development and preparing for future projects
• Methodological development and training
  (workstream supported by core-funding)

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North Wales Organisation for Randomised Trials
in Health (NWORTH)
During
After
Before
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Impact of core funding on capacity building (2)

• Working with others
• Academic clients through grant development
• Research Design and Conduct Services/research
  courses and surgeries in the NHS
• Access to other infrastructure groups (e.g. WHESS
  and Involving People)
• Expansion and sustainability
• Cost-recovery model allows expansion, development
  of critical mass and flexibility to respond to
  changes and initiatives
• Tapered-funding model supports move towards
  self-sustainability

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Other support for capacity building

• Academic Health Science Collaboration Research
  Methodology Support Scheme (CTUs embedded in
  regional hubs)
• Research for Patient and Public Benefit Programme
• NHS focused
• CTUs driving activity at regional level
• Standard competitive programmes Research
  Funding Scheme, Fellowships, Studentships

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Contact details

• For further enquiries please contact
• Michael Bowdery
• NISCHR
• Welsh Government
• Cathays Park, Cardiff CF10 3NQ
• Tel [phone]
• E-mail Michael.Bowdery_at_wales.gsi.gov.uk

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Northern IrelandDanny McAuley
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Current update

• New Director
• Northern Ireland Clinical Trials Unit (NICTU)
• Focus on CTU role
• UKCRC - CTU
• Provisional Registration
• Full Registration

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Previous Organisational Structure
Director
Snr Admin Ass
Database Development ICT Medical Physics Agency
Admin Ass
Gen Admin Ass
Snr Health Economist
Snr Biostatistician
Data Project Manager
QA Manager
Trial Manager
Health Economist
Data Manager
Biostatistician
Research Monitor
Trial Co-ordinator
Data Processor
Jnr Biostatistician
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New Organisational Structure
Director
CTU Manager
Admin Assistant
Personal Assistant
Gen Admin Ass
Snr Statistician
QA Manager
Snr Trial Manager
Data Project Manager
ICT Manager
Snr Health Economist
Snr Research Monitor
Research Monitors
Trial Managers / Trial Co-ordinators
Database Developer
Data Managers
Biostatistician
Health Economist
Data Processors
Jnr Biostatistician
Clinical Trial Admin
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Future Developments

• Development of CTU Team
• Staff development and new staff
• CTU Portfolio
• NIHR funded
• Development of CTU Management Systems