Introduction to ModelMaker

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Introduction to ModelMaker

• Sabine Beulke, CSL, York, UK
• FOCUS Work Group on Degradation Kinetics
• Estimating Persistence and Degradation Kinetics
• from Environmental Fate Studies in EU
  Registration
• Brussels, 26-27 January 2005

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Curve fitting with ModelMaker

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Model construction
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Model components
Compartment Flow
Part of the system with defined boundaries which
can store the quantity of interest (e.g. a
pesticide) Represents the movement of the
quantity from one compartment to another
Parent in soil Metabolite in soil Parent ?
Metabolite
Change of quantity in compartment with
time dCompartment / dt Flows in - Flows out
Variable
Quantity which is a function of other model
components or a function of an independent
variable (e.g. time)
DT50 as a function of other model parameters
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Initial conditions and parameters
For each compartment, the starting point
(quantity present at the beginning of the
simulation) must be defined Parent 100 applied
radioactivity Metabolite zero Parameters are
constants which do not change during the
simulation kparent degradation rate constant for
the parent in soil M0 initial amount of
the parent compound ffM formation fraction
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ModelMaker toolbar
run model
optimise model
create graph
create table
add and define parameters
compartment
flow
variable