The Skeletal System

1
Gross Anatomy of Skeletal Muscle

• Muscle fiber
• Endomysium
• Fascicle
• Perimysium
• Epimysium
• Deep facia

2
Connective Tissue Sheaths

• Endomysium
• Perimysium
• Epimysium
• Collagen fibers of all 3 layers come together at
  each end of muscle to form a tendon or
  aponeurosis.

3
Microscopic Muscle Fiber Anatomy

• Sarcolemma - cell membrane
• Sarcoplasm - cytoplasm
• Myoglobin
• Transverse tubules
• Sarcoplasmic
• Reticulum
• Myofibrils
• - A I Bands
• ? Stripes

4
Myofibril

• Myofilaments
• Two types
• Actin ( 2) filaments (thin filaments)
• Myosin filaments (thick filaments)

5
Actin (Thin) Filament

• Three proteins
• Actin (contractile)
• Troponin (lock)
• Tropomyosin (door)

6
Myosin (Thick) Filament

• 1 protein
• Generates tension

7
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8
Sarcomere

• Between 2 Z-discs
• Contractile Unit
• Sarcomere
• sarcomere
• sarcomere
• myofibril

9
Actin and Myosin Filaments
10
I bands
11
Z lines
Sarcomere