Table. Clinical Efficacy and Safety

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Table. Clinical Efficacy and Safety
Ticagrelor Clopidogrel HR (95 CI) Interaction P-value
CV death, MI, or stroke CV death, MI, or stroke CV death, MI, or stroke CV death, MI, or stroke CV death, MI, or stroke
75 years 17.2 18.3 0.95 (0.781.13) 0.22
lt75 years 8.6 10.4 0.82 (0.740.91) 0.22
All-cause mortality All-cause mortality All-cause mortality All-cause mortality All-cause mortality
75 years 9.8 12.4 0.81 (0.651.03) 0.78
lt75 years 3.6 4.8 0.78 (0.670.92) 0.78
MI MI MI MI MI
75 years 9.3 9.4 0.96 (0.75-1.24) 0.25
lt75 years 5.4 6.6 0.81 (0.71-0.93) 0.25
CV death CV death CV death CV death CV death
75 years 8.1 10.3 0.79 (0.61-1.02) 0.90
lt75 years 3.3 4.2 0.81 (0.68-0.95) 0.90
Definite stent thrombosis Definite stent thrombosis Definite stent thrombosis Definite stent thrombosis Definite stent thrombosis
75 years 1.8 2.1 0.66 (0.31.45) 0.94
lt75 years 1.3 1.9 0.67 (0.490.93) 0.94
Overall major bleeding Overall major bleeding Overall major bleeding Overall major bleeding Overall major bleeding
75 years 14.2 13.5 1.04 (0.841.28) 1.00
lt75 years 11.2 10.8 1.04 (0.941.15) 1.00
Non-CABG major bleeding Non-CABG major bleeding Non-CABG major bleeding Non-CABG major bleeding Non-CABG major bleeding
75 years 8.3 7.1 1.16 (0.871.55) 0.78
lt75 years 3.9 3.2 1.22 (1.021.46) 0.78