Granulation

1
Granulation

• done to
• improve flow properties of the mix
• improve compression properties of the mix
• prevent segregation of components in powder mix
• reduce production of toxic dust
• reduce possibility of cake formation
• increase convenience of transport

2
Granulation

• particle bonding mechanisms
• adhesion and cohesion forces in immobile liquid
  films
• interfacial forces in mobile liquid films
• solid bridges
• attractive forces between solid particles

3
Granulation

• Wet granulation equipment
• 3 main types
• shear granulators
• high speed mixer/granulators
• fluidized bed granulators
• shear granulator

4
Wet Granulation

• high speed mixer/granulator

5
Wet Granulation
fluidized bed granulator
6
Wet Granulation

• other more specialized granulators
• spray driers

7
Wet Granulation

• pelletizers

8
Dry Granulation

• Dry granulation equipment
• sluggers
• roller compactors