Teratoma

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Teratoma

• Dr. Venkatesh M Shashidhar
• Senior Lecturer in Pathology
• Fiji School of Medicine

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Germ cell Tumors

• Dysgerminoma No differentiation
• Yolksac tumor Extra-embryonic diff.
• Choriocarcinoma Trophoblastic diff.
• Embryonal Carcinoma Primitive diff.
• Teratoma Somatic tissue differentiation

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Teratoma

• Most common Germ cell tumor
• Majority are benign cystic reproductive age
• Minority are solid malignant Prepuberty
• Origin meiotic germ cell parthenogenesis

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Teratoma Types

• Mature teratoma - Benign cystic
• Immature teratoma Malignant, Solid
• Monodermal or Specialised single tissue

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Mature Teratoma

• Young reproductive age
• Cystic
• Benign
• Ectodermal differentiation (Dermoid cysts)
• About 1 - malignancy Squamous Ca.
• Rarely solid with mature tissues Benign.

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Cystic Teratoma
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Dermoid Cyst
mamillae or Rokitansky's protuberances
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Mature Cystic Teratoma
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Cystic Teratoma
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Mature Cystic Teratoma
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Mature Cystic Teratoma
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Dermoid Cyst
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Immature Teratoma

• Rare
• Fetal or embryonic tissues
• Prepubertal young adolescents
• Large bulky tumors, solid
• Areas of necrosis, hemorrhage
• Embryonic tissue maturing to different tissues
  cartilage, bone, muscle, nerve etc.
• Break capsule, spread, metastasis.

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Immature Teratoma - Testes
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Monodermal or specialized

• Rare
• Struma ovarii Thyroid - hyperthyroidism
• Carcinoid Intestine - Carcinoid syndrome
• Strumal carcinoid combination
• Rarely malignant (lt2)

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Dysgerminoma - Ovary
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Dysgerminoma - Ovary
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Normal Ovary