The enzyme, fumarase, has the following kinetics constants:

1
Fumarase
The enzyme, fumarase, has the following kinetics
constants
where k1109 M-1s-1, k-14.4X104 s-1, k2 103 s-1
a. What is the value of the Michaelis constant
for this enzyme? What is the Km in BH approach?
b. At an enzyme concentration of 10-6 M, what
will be the initial rate of product formation at
a substrate concentration of 10-3M? Calculate
them using the two approaches.