Premedication

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Premedication

• Dr.M.Kannan MD DA
• Professor And HOD
• Department of Anaesthesiology
• Tirunelveli Medical College

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Premedication

• Drugs administer 1-2 hours before induction of
  Anaesthesia

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Why Premedication

• To Allay anxiety and fear
• Non Pharmacological
• -Assurance Raport
• Pharmacological
• -Benzodiazepanies
• -Diazepam
• -Medazolam
• -Lorozepam

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Why Premedication

• To Reduce Secretion
• Salivary secretion
• Broncheal secretion
• Anticholinergic drug-Atropine
• -Glycopyrolate
  
• Tachycardia Hyperthermia

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Why Premedication

• Enhances Hypnotic effect of General Anaesthetic
  Drugs
• -Less amount volatile Anaesthetics and nacotics

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Why Premedication

• Reduces Postoperative Nausea and Vomiting
• Aspiration
• Psychological trauma

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To Prevent Vomiting

• Metachlorpropamide
• Ondansetron
• Ranitidine

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Why Premedication

• Produce Amnesia
• Benzodiazepine group
• -Diazepam 0.1-0.2mg/kg
• -Medazolam0.05mg/kg
• -Lorozepam

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Why Premedication

• Gastric Content Volume ph -alkaline
• Metoclopramide-
• Sodium citrate

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Why Premedication

• Attenuate sympathetoadrenal response
• -Laryngoscopy

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Why Premedication

• Attenuate vagal reflex
• ? Bradycardia
• Traction of eye muscle
• in squint surgery
• Repeated administration succinylcholine
• -Induction of Anaesthesia with halothane
• -Lighter plane of Anaethsia

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Why Premedication

• Allay anxiety and fear
• Reduce Secretion
• Enhances Hypnotic effect of General Anaesthetic
  Drugs
• Reduces Postoperative Nausea and Vomiting
• Produce Amnesia
• Gastric Content Volume ph -alkaline
• Attenuate vagal reflex
• Attenuate sympathetoadrenal response

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What Drugs ?

• Antisailagoge Atropine/Glycopyrolate
• Sedative Morphine
• -Pethedine
• -Benzodiazepaines
• -Barbiturates
• Antiemitics -Metachlorpropamide/Ondonsetron
• Disease Specific Drugs

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Can we Give Fixed Pre.Med

• NO
• Cardiac Avoid anticholinergics Stiff
  sedatives
• Thyrotoxicosis- Avoid anticholinergic
• Head injury- Avoid sedatives
• Airway obstruction- Aviod sedatives
• Pregnancy- Avoid sedatives