Environmental and nutritional diseases

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Environmental and nutritional diseases
SYLLABUS RBP(Robbins Basic Pathology)
Chapter Envinronmental diseases
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Environmental and nutritional diseases

• Colloid goiter
• Melanoma
• Anthracosis
• 35a Asbestosis
• s43 Dental caries

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Colloid goiter

• Enlarged, colloid-rich gland
• the follicular epithelium flattened and cuboidal
• abundant colloid

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Colloid goiter
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Colloid goiter
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Melanoma
Nests of neoplastic cells predominant in lower
epidermis and single cells in upper epidermis.
Cells with pleomorphic nuclei, abundant pale
cytoplasm and dusty melanin with epithelioid or
spindle cell morphology. Mitotic figures usually
present. Variable features include inflammatory
infiltrate, ulceration of skin, and amount of
melanin.
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Melanoma
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Melanoma
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Anthracosis
coal macules and coal nodules - carbon-laden
macrophages - nodules also contains small
amounts of a delicate network of collagen
fibers - sometimes centrilobular emphysema
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Anthracosis
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Anthracosis
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Asbestosis

• interstitial pneumonitis and (rarely)
  desquamative interstitial pneumonitis
• progressive massive fibrosis
• pleuritis
• pathognomonic finding - the asbestos body - an
  asbestos fiber coated with iron-containing
  material (rodlike and beaded, variable length,
  translucent gold color with hollow appearing
  central core, possibly bulbous swellings at ends
  or along midportion)

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Asbestosis
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Asbestosis
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Dental caries

• Focal degradation of the tooth structure
• the result of mineral dissolution of tooth
  structure by acid metabolic end products from
  bacteria that are present in the oral cavity and
  are capable of fermenting sugars

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Dental caries
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Dental caries