NITROGLYCERIN

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NITROGLYCERIN
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Nitroglycerin

• Indications
• Ischemic Chest Pain

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Nitroglycerin

• Contraindications
• BPlt100mm Hg
• Pt. Has already taken maximum dose of three doses
  (1.2mg)

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Nitroglycerin

• Dose
• .4mg sublingual
• Tablet or Metered-dose Spray
• .4mg Trans-dermal patch
• May repeat at 5 minute intervals up to 3 doses
  (1.2mg)

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Nitroglycerin

• Mechanism of Action
• Relaxes vascular smooth muscle

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Nitroglycerin

• Effects
• Decreased pre-load
• Decreased after-load
• Increased blood flow to Ischemic Myocardium

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Nitroglycerin

• Side Effects
• Hypotension
• Reflex Tachycardia
• Headache

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Nitroglycerin

• Comments
• Most effective when Pt is sitting
• If tablet form - Protect potency
• Store in original brown bottle
• Keep tightly sealed
• Protect from light, air, heat
• Secure new supply every 4 - 6 months

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Nitroglycerin

• Potent Nitroglycerin
• Headache
• Burning sensation under tongue