Patrick

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Patrick An Introduction to Medicinal Chemistry
3/e Chapter 9 DRUG DISCOVERY FINDING A
LEAD Part 3 Section 9.4 (Lead compounds from
the synthetic world)
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Contents Part 3 Section 9.4 - Lead compounds
from the synthetic world 4.4. Lead Compounds
from the Synthetic World - Organic
Synthesis - Combinatorial Synthesis - Combinat
orial Synthesis - Peptide Synthesis - Combinator
ial Synthesis - Heterocyclic Synthesis (5
Slides) 14 slides
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4.4 Lead Compounds from the Synthetic World
SYNTHETIC COMPOUNDS
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4.4 Lead Compounds from the Synthetic World
PRONTOSIL
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4.4 Lead Compounds from the Synthetic World
SULFANILAMIDE
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4.4 Lead Compounds from the Synthetic World
TNT
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4.4 Lead Compounds from the Synthetic World
RUBBER INDUSTRY
ANTABUSE
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4.4 Lead Compounds from the Synthetic World
ORGANIC SYNTHESIS
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4.4 Lead Compounds from the Synthetic World
COMBINATORIAL SYNTHESIS
AUTOMATED SYNTHETIC MACHINES
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4.4 Lead Compounds from the Synthetic World
COMBINATORIAL SYNTHESIS - PEPTIDE SYNTHESIS
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4.4 Lead Compounds from the Synthetic World
COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS
RESIN BEAD
N
N
O
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4.4 Lead Compounds from the Synthetic World
COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS
N
N
O
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4.4 Lead Compounds from the Synthetic World
COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS
N
N
O
EtO
O
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4.4 Lead Compounds from the Synthetic World
COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS
N
N
N
HN
O
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4.4 Lead Compounds from the Synthetic World
COMBINATORIAL SYNTHESIS - HETEROCYCLIC SYNTHESIS
RESIN BEAD
N
N
N
HN
O