Logic programming steps towards formal biology. Fran ois Fages, ... Elucidation of high-level ... word of m a-helix, b-strands, random coils,... (3m-10m) ...
Develop new formalisms, languages and algorithms coming from biological ... Multidisciplinary field aiming at getting over the complexity walls to reason ...
Version 7.2 en fran ais (22 diapos) Version anglaise en pr paration ... Hybrid Systems: A First Experiment in Systems Biology Fran ois Fages, INRIA Rocquencourt
Mod lisation math matique classique de syst mes dynamiques non-lin aires ... le processus de d gradation est actif. G1. G1. S. G2. M. MPF. SPF. temps. Concentration. des ...
Qualitative properties formalized in ... Study the concentration of chemical substances in a biological system as ... the system of ODEs over variables {A1 , ...
Constraint-Based Linear Time Logic. Constraints over concentrations and derivatives as FOL ... Hypothesis 2: the formula can be checked over a finite period of time [0,T] ...
production of one complementary strand for each copy. Fran ois Fages ... [Shankar 93] to rules (asynchronous) over-approximating the set of all possible ...
which correctly over-approximates the set of all possible behaviors ... Which are the states from which a set of products P1,. . . , Pn can be produced ...
A knowledge based approach for representing, reasoning and ... Initial condition I = { intially f } Observation O = { eventually g } (K,I) does not entail O ...
Reaction rules with continuous time dynamics [Fages-Soliman-Chabrier 04] ... Necessary for over-approximating the possible behaviors under the stochastic ...
'Systems biology is the coordinated study of biological ... Human, rat and canine expression profiles of just under 40 genes have been examined thus far. ...
Find parameters for which a fast and high-amplitude response to aTc is robustly obtained ... and high-amplitude response to aTc. 2) ODE model with Hill ...
Director, Midlands e-Science Centre on Modelling and Analysis of Large Complex Systems ... Rigorous foundation for modelling dynamics of biological systems ...
... S transition in the mammalian cell cycle. From a qualitative network to a kinetic ... eigenvalues are functions of cycles only. 50. Hurwitz determinants D1 = a1 ...