There are an increasing number of encyclopedic' metabolic ... Dan Davison. Anamika Kothari. Joseph Dale. MetaCyc.org. 13. SRI International Bioinformatics ...
Pathway Tools / BioCyc Fundamentals Peter D. Karp, Ph.D. Bioinformatics Research Group SRI International pkarp@ai.sri.com BioCyc.org EcoCyc.org, MetaCyc.org, HumanCyc.org
Challenges in Creating and Curating Plant PGDBs: Lessons Learned from AraCyc and PoplarCyc Peifen Zhang Carnegie Institution For Science Department of Plant Biology
A Bioinformatics Database Warehouse Peter D. Karp, Thomas J. Lee, Valerie Wagner BioCyc BioPAX BioCyc ENZYME CMR Genbank BioWarehouse Eco2DBase Oracle (10g) or
Selected PathoLogic Refining Tasks Creation of Protein Complexes Assignment of Modified Proteins Operon Prediction Creating Protein Complexes Refine - Create Protein ...
Why Curate a PGDB? A well curated PGDB can serve as a central online resource that integrates many ... Curate full information for enzymes and genes. ...
Introduction to Bioinformatics - Tutorial no. 13 Probe Design Gene Networks Probe design problem Given a genome with a set of genes. Recall that each gene is ...
In silico reconstruction of the metabolic pathways of ... determine orthology (use phylogeny and gene-context to determine evolutionary relationship) ...
... you to specify additional name-reaction mappings not present in ... The name matcher indexes names from: reaction frames (e.g., official names assigned by EC) ...
Biological Pathways ... PPI databases Many databases DIP Established in 1999 in UCLA extract and integrate protein-protein info and build a user-friendly ...
Title: Protein Family Classification for Functional Genomics Author: wuc Last modified by: zh9 Created Date: 3/9/2001 10:06:29 PM Document presentation format
What do you hope to get out of the tutorial? SRI International. Bioinformatics. SRI ... Mike McLeod, University of British Columbia, Rhodococcus sp. RHA1 ...
With the advent of high-throughput methods, we dispose of ... ChIP (Chromatin Immunoprecipitation) on chip to detect protein-DNA binding. Mutant phenotypes. ...
By name/frame ID must be exact (though there are synonyms) ... Synonyms, classification (GO), link to browser. Unification links, gene-reaction schematic ...
All pathways are networks of interactions, however not all networks are ... Chemical substructure comparison. Enzymes,Transcription Factors. Genes: Blast search ...
The database is separate from the user interface. The Navigator ... Curate information about enzymes and genes, including evidence codes for all enzymes. ...
Identification of Intracellular Metabolites in Shewanella oneidensis MR-1 upon Salt Stress ... pp. 79-97. Proline. Glycine Betaine. Glutamate. Common osmoprotectants ...
Chemical substructure comparison. Enzymes, Transporters, ... Query compounds by name, MW, formula, substructure. Reference list displayed at bottom of page ...
Global changes in Staphylococcus aureusgene expression during human prosthetic joint infection. AAU. trt@teknologisk.dkwww.cmc.aau.dk. I n t r o d u c t i o n
Pathways are just one of the types of data we provide, and they account for a ... Found that it was easier to make progress by making a focused 'project' out of ...
Systems biology ...not in ten years. Pathways which? ... Tautomerism (variable positions of hydrogens) Other 'chemical' flexibility. Protonation state ...
Definition of Bioinformatics ... For many years, the majority of bioinformatics DBs did not employ a DBMS ... Warehouse schema defines many bioinformatics datatypes ...
... Knowledge Representation Systems. Long history of development in the AI knowledge ... Aka DB, Knowledge Base, KB, PGDB. An Ocelot database is a ...
Digital Cells Nano-Bio-Info Technology Introduction to Nanotechnology Image by John Alsop Outline Concept of a gene (extended) Gene Regulatory Networks (GRN) GRN and ...
Types of Credit: Created, Reviewed, Revised. Home Pages for Authors ... used for Stoichiometry Coefficients, Compartments, Citations, etc. Principal Classes 1 ...
'Creating the right chemistry' in Pathways. M.A. Ott. Enzymes don't ... FAD, FADH2. FMN, FMNH2. SAM, SAH. Coenzyme A. Glutamate/2-Oxoglutarate. Phosphorylation ...
Drawing, clustering and visualization of biological pathways. ... David Auber (Bordeaux Labri) Yves Chiricota (Chicoutimi UQAM) Thank you for your attention ...
RGD (Rat), Medical College of Wisconsin. WormBase (C. elegans), Caltech. Large scale users: ... Will use dictionary of biomedical terms. New sequence retrieval dialog ...
Create a toolkit for integrating a set of bioinformatics databases into one ... Representational tricks to decrease schema bloat. Single space of primary keys ...
... gene products with GO terms (annotation) GO employs three ontologies to describe gene product attributes: ... NUTRITIONAL COMPOSITION. DIET GO. RELATED PRODUCTS ...
Database concepts - what is a 'good' database (DB) How is data stored and ... has open interfaces (APIs) for query requests. Bad DB: ... APIs, Mashups, SQL ...