Title: What Is Piperazine Derivatives? Guide By Shree Ganesh Chemicals
1WHAT IS
PIPERAZINE DERIVATIVES ?
2021
GUIDE AND ITS'VARIOUS USES
2ABOUT US
GANESH CHEMICALS IS PHARMACEUTICALS INTERMEDIATES
AND CHEMICALS MANUFACTURERES , ANKLESHWAR - INDIA
Shree Ganesh Chemicals One Of The Leading
Pharmaceuticals Intermediates And Specialized
Chemicals, Ankleshwar Working Since 1999. We use
state of an art manufacturing facilities to
produce top-quality pharmaceuticals intermediates
(APIs) and specialized pharma chemicals. Our
Experts team uses innovative methods to produce
pure chemicals for clients. SGCs have the right
experience to offer effective custom chemistry
services. Our products comply with all the
necessary standards and our frequent quality
testing ensures that we deliver only flawless
products to our customers.
3PIPERAZINE DERIVATIVES
General Information, properties And Uses
4GENERAL INFORMATION
PIPERAZINE DERIVATIVES
Piperazine is an organic compound that consists
of a six-membered ring containing two nitrogen
atoms at opposite positions in the ring.
Piperazine exists as small alkaline deliquescent
crystals with a saline taste. The piperazines are
a broad class of chemical compounds, many with
important pharmacological properties, which
contain a core piperazine functional
group. Piperazine is freely soluble in water and
ethylene glycol, but insoluble in diethyl ether.
It is a weak base with two pKb of 5.35 and 9.73
at 25 C. the pH of a 10 aqueous solution of
piperazine is 10.811.8. Piperazine readily
absorbs water and carbon dioxide from the air.
Although many piperazine derivatives occur
naturally, piperazine itself can be synthesized
by reacting alcoholic ammonia with 1,2-
dichloroethane, by the action of sodium and
ethylene glycol on ethylene diamine
hydrochloride, or by reduction of pyrazine with
sodium in ethanol. A form in which piperazine is c
ommonly available industrially is as the
hexahydrate, C4H10N2. 6H2O, which melts at 44 C
and boils at 125130 C. Industrial
production Piperazine is formed as a co-product
in the ammoniation of 1,2-dichloroethane or
ethanolamine. These are the only routes to the
chemical used commercially. The piperazine is
separated from the product stream, which contains
ethylenediamine, diethylenetriamine, and other
related linear and cyclic chemicals of this type.
5PROPERTIES
C A S N U M B E R 1 1 0 - 8 5 - 0
C 4 H 1 0 N 2 G M O L - 1 C R Y S T A L L I N
E S O L I D 3 7 9 K )
C H E M I C A L F O R M U L A
8 6 . 1 3 8 W H I T E
M O L A R M A S S A P P E A R A N C E
M E L T I N G P O I N T B O I L I N G P O I N
T
1 0 6 C ( 2 2 3 F
4 6 C ( 2 9 5 F 4 1 9 K ) S U B L I M A T E
S
S O L U B I L I T Y I N W A T E R F R E E L Y S O L U B L E 2
A C I D I T Y ( P K A ) 9 . 8
B A S I C I T Y ( P K B ) 4 . 1 9
M A G N E T I C S U S C E P T I B I L I T Y ( ? ) - 5 6 . 8 1 0 6 C M 3 / M O L
6USES
P I P E R A Z I N E H Y D R A T E , P I P E R A
Z I N E A D I P A T E A N D P I P E R A Z I N
E C I T R A T E ( U S E D T O T R E A T A S C A
R I A S I S A N D E N T E R O B I A S I S 7
) A R E T H E M O S T C O M M O N A N T H E L M I
N T I C P I P E R A Z I N E C O M P O U N D S
. T H E S E D R U G S A R E O F T E N R E F E
R R E D T O S I M P L Y A S " P I P E R A Z I N
E " W H I C H M A Y C A U S E C O N F U S I O N B
E T W E E N T H E S P E C I F I C A N T H E L M I
N T I C D R U G S , T H E E N T I R E C L A S S O
F P I P E R A Z I N E - C O N T A I N I N G C O
M P O U N D S , A N D T H E C O M P O U N D I T S
E L F . D I E T H Y L C A R B A M A Z I N E , A D
E R I V A T I V E O F P I P E R A Z I N E , I S U
S E D T O T R E A T S O M E T Y P E S O F F I L
A R I A S I S . O T H E R U S E S P I P E R A
Z I N E S A R E A L S O U S E D I N T H E M A N U
F A C T U R E O F P L A S T I C S , R E S I N S
, P E S T I C I D E S , B R A K E F L U I D A N
D O T H E R I N D U S T R I A L M A T E R I A L
S . P I P E R A Z I N E S , E S P E C I A L L
Y B Z P A N D T F M P P W E R E E X T R E M E L
Y C O M M O N A D U L T E R A N T S I N T H E C
L U B A N D R A V E S C E N E , O F T E N B E I
N G P A S S E D O F F A S M D M A , A L T H O U G
H T H E Y D O N O T S H A R E M A N Y S I M I L
A R I T I E S I N T H E I R E F F E C T S . P I
P E R A Z I N E I S A L S O A F L U I D U S E D F
O R C O 2 A N D H 2 S S C R U B B I N G I N A S
S O C I A T I O N W I T H M E T H Y L D I E T H A
N O L A M I N E ( M D E A ) .
7Piperazine Derivatives Manufacturers
Shree Ganesh Chemicals Is A Leading Piperazine
Derivatives manufacturers are considered as Top
Piperazine Derivatives manufacturer and
Exporter. Piperazine Derivatives are our Top most
products as drug intermediates. SGCs are counted
among the leading manufacturers and exporters of
piperazine derivatives worldwide. SGC is one of
the most renowned piperazine manufacturers and
piperazine exporters in India And Worldwide. We
make fine quality piperazine hydrochloride for
several clients. Piperazine Derivatives are our
top products as drug intermediates. We
manufacture chemicals, including piperazine
derivatives and supply them to many other
countries as well.
8PIPERAZINE DERIVATIVES HAVE MANY APPLICATIONS.
OUR MANUFACTURE AND EXPORT BY US AS MENTIONED
BELOW
1 - ( 3 - C H L O R O P H E N Y L ) P I P E R I
Z A N E H Y D R O C H L O R I D E
1 - A C E T Y L - ( 4 - H Y D R O X Y P H E N Y L
) P I P E R A Z I N E
1 - ( 3 - C H L O R O P H E N Y L ) - 4 - ( 3 -
C H L O R O P R O P Y L ) P I P E R A Z I N E H Y
D R O C H L O R I D E
Case No 870-24-6
Case No 13242-
Case No 1942-52-5
API/Enduse Ketcanazole
API/Enduse
Tramadol
API/Enduse Trazadone
9M A I L I N G A D D R E S S
Plot No. 6708-6711,GIDC Estate,
Ankleshwar-393002,Gujarat, India P H O N E N U M
B E R 91 9638786186
CONTACT INFO
E M A I L A D D R E S S info_at_shreeganeshchemical.c
om
10THANK YOU...