Prion Disease PowerPoint PPT Presentations

Communicable Diseases, Nosocomial Diseases, Emerging and ReEmerging Diseases

Prion Diseases Garrett Preston Clark, D.O.

Prion proteins THE 'protein only' hypothesis' states that a modified form of normal prion protein triggers infectious neurodegenerative diseases, such as bovine ...

PRION DISEASE & PENTOSAN POLYSULPHATE IN THE UK Richard Knight NCJDSU University of Edinburgh Scotland * * * * * * * * * * * * * * * * * Although CJD patients have ...

... Bovine Spongiform Encephalopathy (BSE) (Feline & Ungulate), Scrapie, Chronic Wasting Diseases (CWD), Transmissible Mink Encephalopathy. In Humans ...

Ataxia: cerebellar dysfunction, including muscle incoordination,gait and speech abnormalities. ... and symptoms: cerebellar ataxia, gait abnormalities, dementia, ...

[PDF] Prions and Mad Cow Disease Full- Copy URL | gooread.fileunlimited.club/pw23/0824740831

Prion Diseases Kuru Kuru figures Incidence 1 % (population aprox. 15,000) total F : M = 10 : 1

... (TSE) Neurodegeneration, vacuolation, and deposition of ... TSE vacuolation scoring. PrPSc typing by Western blot. PrPSc detection by immunocytochemistry ...

PRIONS diseases

Transmissible Mink Encephalopathies (TME)- mink. Animal TSE's and ... TME- found in ranched mink so has an impact on fur sales. More TSE's and Animals. Scrapie ...

less complex particle than virus. as infectious agent. capable ... Feline spongiform encephalopathy. BSE (Mad cow disease) Chronic wasting disease in deer, elk ...

Prion disease is also known transmissible spongiform encephalopathy is characterized by rare progressive neurodegenerative disorders of brain. Spongiform encephalopathy is a disease where the brain tissue degenerates and healthy tissues gets replaced by clusters of tiny liquids filled, thin-walled cavities called cysts making the brain looks like sponge.

Infection within some wild animal populations, like Elk and Deer, is rapidly spreading. ... False color image of a mouse heart infected with Scrapie. ...

1. Degenerative nervous system diseases with very long ... Bovine Spongiform Encephalopathy (BSE) aka Mad Cow Disease. Feline spongiform encephalopathy ...

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Rabies Poliomyelitis Prion Disease Nani Kurniani, dr., SpS(K) Dept. of Neurology Hasan Sadikin Hospital Bandung ...

Motor Disease Alzheimer Disease

Rabies Poliomyelitis Prion Disease Nani Kurniani, dr., SpS(K) Dept. of Neurology Hasan Sadikin Hospital Bandung ...

... brachial plexopathy, mononeuritis) Myopathies myopathy, myositis AIDS tumors Primary lymfoma of CNS (PCNSL) most frequent, children, adult ...

Prion Disease is a disease in which a kind of protein that triggers normal proteins in the brain and makes it to fold abnormally.

(may also be protracted course of disease) multiple neurological symptoms. 3 ... human cadaver growth hormone. human cadaver gonadotropin. dural mater grafts ...

A protein particle that lacks nucleic acid and is sometimes held to be the cause ... BSE (bovine spongiform encephalopathy): cows - first noticed in 1986 in England. ...

Bovine Spongiform Encephalopathy. Scrapie. SPORADIC CJD. The most common form of CJD ... Bovine Spongiform Encephalopathy. First described in the UK in 1986 ...

Mad cow disease is a neurological disease in which certain abnormal proteins known as prions induce the formation of lesions/plaques in the brain tissue of the infected animal.

However, its levels in body fluids and tissues other than nervous system are too ... Buffy coat 0.05-0.1 pg/ml = 1-2 x 107 molecules. Can we detect PrPSc in blood? ...

weakness. speech problems. cognitive problems. headaches. gait problems ... tremors, ataxia, weakness. dementia, death. amyloid plaques. spongiform changes ...

This is a Seminar "Molecular Dynamics (MD), Quantum Mechanics / Molecular Mechanics (QMMM), and Molecular Modeling (MM) Studies of Prion Proteins and Prions "for the journal Biochemistry & Pharmacology: Open Access

Is the infectious prion protein PrPsc present in blood of variant Creutzfeldt ... chronic wasting disease; FSE, feline spongiform encephalopathy; HGH, human ...

Prions Properties Diseases Distinctive characteristics

Prion Lecture Week 11 Medical Microbiology SBM 2044 Prion Diseases Prion diseases are associated with the accumulation in the CNS of an abnormal form of a host ...

No machinery for energy generation of protein synthesis. Different from viruses ... Transmissible mink encephalopathy. Chronic wasting disease of mule deer ...

Diseases Animals to Humans (Zoonotic Diseases) Georgia Agricultural Curriculum Office By: Jennifer Osborne, Katrina Kennedy, and Dr. Frank Flanders

Title: DISEASE EMERGENCE AND RE-EMERGENCE Author: Roger Detels Last modified by: Wendy Aft Created Date: 3/27/2004 8:05:16 PM Document presentation format

Fleas. Ticks. Nonliving. Prions Mad cow disease, scrapie, JCD. Classifying Infectious Diseases ... Symptom A change in body function that is felt by a patient ...

CJD and Kuru: Prion Viruses By: Danny Nemeth Prion infectious agent composed of protein in a misfolded form CJD Creutzfeldt-Jakob Disease neurodegenerative disorder ...

define the characteristics of a prion including the proteinase- resistance, ... the agent is first recoverable from lymphoid tissues (tonsil mesenteric LN) ...

Disease Detectives B/C What is Disease Detectives? Epidemiology: Study of health/sickness of populations Includes Public Health Surveillance Data collection for ...

Enteroviruses cause a variety of diseases including, febrile illnesses, and ... Kuru. Prions. Infectious proteins. Normally found on surface of mammalian cells ...

Mad Cow Disease

Infectious Disease Infectious Disease Globally, Infectious disease is still the single most common cause of death in 1993, 16 million people died from infectious ...

Description of the disease process. Possible etiology based on population studies. ... Prion, Parkinson? and Huntington? diseases all cause dementia. ...

INFECTIOUS DISEASES

Chapter 22 Microbial Diseases of the Nervous System Fungal and Protozoan Diseases The Nervous System Bacterial Diseases Prion Diseases Viral Diseases

Symptoms: Hunters should be very suspicious of 'lazy' rabbits which are easily killed ... Rubber gloves should probably be worn when dressing rabbits. ...

Viruses, Viroids, and Prions Bits and Pieces that cause disease Viruses Viruses contain DNA or RNA and a protein coat Some are enclosed by an envelope Some viruses ...

Chapter 13 Viruses, Viroids, and Prions The Spread and Patterns of Disease Viral Infections Prions/Viroids Epidemiology Viral Characteristics $100

small ruminants common diseases

Viral History Discovery of Viruses Beijerinck ... A virus is a non-cellular particle made up of genetic material and protein that can invade living cells.

Prevention by smallpox vaccination. Poxviruses. Figure 21.9. Varicella-zoster virus (Human herpes virus 3) Transmitted by the respiratory route ...

Prion-Associated Disease ... Hypothesis for Prion Action. Accumulated abnormal proteins kill neuron, with prions spreading to adjacent neurons. ...

In 2000, 7 percent of those with AD were age 65-74, 53 percent ... Distinction between palliative and preventative. Current treatment is Donepezil (Aricept) ...

pathogenesis of many neurodegenerative disorders is due to abnormal protein conformation. common theme in diseases is conversion of normal ... cataracts ...

Sheep Disease Schemes

Viruses and Cancer Viruses and Cancer Viruses to know something about Herpes Simplex HPV human papilloma virus No Slide Title HIV human immunodeficiency virus ...

Progressive supranuclear palsy: oculomotor dysfunction (impaired vertical eye ... of pharyngeal muscles (pseudobulbar palsy); early falls; axial rigidity (neck ...