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Adrenergic drugs, also named as sympathomimetic drugs stimulate a response from the adrenergic receptors. This drug is used to stimulate the sympathetic nervous system located in the chest and lower back region of the spinal cord. These drugs stimulate the chemical messenger epinephrine and norepinephrine from the adrenal gland, or replicate the action of these chemical messengers. There are five main categories of adrenergic receptors as α₁, α₂, β₁, β₂, and β₃. Adrenergic drugs are used to increase the breathing rate, heartbeat, sweating, urine flow, and prevent bleeding. There are three major types of adrenergic drugs most commonly used such as Bronchodilators, vasopressors, and cardiac stimulators. This drug is used in the treatment of various life-threatening conditions including chronic obstructive pulmonary diseases (COPD), asthma, cardiac arrest, shock, and allergic reactions.
¢ Drug interactions of Meglitinides (Repaglinide & Nateglinide) are dealt in this presentation. ¢ Repaglinide is metabolized by the CYP3A4 and CYP2C8 and hence it interacts with Gemfibrozil, Azole antifungals, Dabrafenib, Montelukast, Macrolide antibiotics and Rifampicin. ¢ Nateglinide is metabolized by CYP2C9 (70%) and CYP3A4 (30%) and it interacts with Amiodarone and Macrolide antibiotics. It also interacts with NSAIDs, MAOIs, Trandolapril, Non selective beta blockers Thiazide diuretics, Corticosteroids, Danazol, Sympathomimetics, Phenytoin and St.John’s wort.
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Title: Toxidromes Last modified by: Eugene Chubmkov Document presentation format: On-screen Show Other titles: Arial Times New Roman Default Design Toxidromes ...
Anatomy of Sympathetic (thoracolumber) Nervous System Nerves arise from spinal cord Pre-ganglionic nerve fibers arise from thoraco-lumber region of sp.cord (T1-L2 ...
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