aaacacTTGA TActgtatga gcatacagTA TAATtgcttc Aacagaacat attgactatc c - PowerPoint PPT Presentation

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aaacacTTGA TActgtatga gcatacagTA TAATtgcttc Aacagaacat attgactatc c

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activates some promoters when glucose is absent. bind to promoter. lexA repressor protein. represses promoters of DNA-repair genes ... – PowerPoint PPT presentation

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Title: aaacacTTGA TActgtatga gcatacagTA TAATtgcttc Aacagaacat attgactatc c


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recA promoter (binds sigma 70) -- sequence from
www.ecocyc.com
aaacacTTGA TActgtatga gcatacagTA TAATtgcttc
Aacagaacat attgactatc c
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-10
-30
transcription start
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DNA
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  • cAMP activated protein
  • activates some promoters when glucose is absent

bind to promoter
binding motif (recognized sequence)
binding domain on the protein
Note these diagrams are called sequence logos
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Sea Urchin Development Network Davidson, et al.,
Science, 2002
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Sea Urchin Promoter (development regulation)
E. coli promoter (glucose transporter regulation)
Combinatorial regulation in bacteria is
underappreciated
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