Organization of the hippocampal circuit

1
Organization of the hippocampal circuit
2
Group Presentation Assignments (last names) (a)
Each group should select a project manager who
will be responsible for coordinating the
assignment (b) One person will present for the
group (20 minute presentation) (c) Written report
must be submitted in class on date of
presentation. An email copy must be sent to Dr.
Ghosh on the same day for posting. Group 1
Yang-Zhang Group 2 Tran, D.-Woo Group 3
Sokotoff.-Tran, C.H. Group 4 Quintel-Smith Group
5 Ng-Purificacion Group 6 McIlvena-Murray Group
7 Kim-McGill Group 8 Hwang-Khan Group 9
Gomez-Huang Group 10 Egbuonye-Gaidarenko Group
11 Chan-Daggett Group 12 Akotia-Brisson
3
Trial Group 1
P 0.0289
4
Trial Group 2
P 0.5838
5
Combined data (Trial groups 1 and 2)
P 0.0442
6
Medial Temporal Lobe Lesion in patient HM
7
(No Transcript)
8
Hippocampal Connectivity in the CNS
Somatosensory
Visual
Olfactory
Sensory Regions Of Cortex
Auditory
Perirhinal Cortex
Perirhinal/ Entorhinal Cortex
Entorhinal Cortex
CA3
Hippocampal Formation
Dentate Gyrus
CA1
9
Hippocampal Output Pathway Intrinsic Circuit
A
B
Entorhinal Cortex
Perforant Pathway
Dentate Gyrus
Mossy Fibers
C
CA3
Schaffer Collaterals
CA1
Amygdala, Cortex
Subiculum/ Entorhinal Cortex
Lateral Septum
10
(No Transcript)
11
Organization of a neuron
12
Spines are sites of synaptic input
13
Ultrastructure of synapses
14
Types of neuronal activity
15
Information is carried via action potentials
16
Membrane depolarization induces action potentials