AndrewsDalkilic

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Andrews-Dalkilic
Data Exploration
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Outline

• Architecture
• What is Bioinformatics?
• Explore some bioinformatics problems and tools
• Talk about whats in store for us
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Architecture
Knowledge Base RULES
Working Memory FACTS
Explanation
Knowledge Acquisition
UI
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Architecture
Knowledge Acquisition
A (semi)automatic way to add domain knowledge
(rules) without having to be a programmer We can
create rulesbut virtually no facility to explain
how and why.
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Architecture
Factoids
Rule-based Systems
Rules
Inference Engine
Efficient Pattern Matching
RHS Execution
Post Production
Conflict Resolution
Markov Rete Bayesian
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Architecture
Post Production
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Architecture
Bertrand Russell said, The point of philosophy
is to start with something so simple as not to
seem worth stating, and to end with something so
paradoxical that no one will believe it.''

• Premises (facts)
• Axiomization Inference Rules
• build
• tear apart

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Architecture
Premises (facts) Questions Are these facts
consistent? existing systems Is this model
consistent with the data? existing systems
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Architecture

• Axiomization Rules
• build
• tear apart

Axiomization is meta-language over the facts
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Architecture
Premises (facts) Axiomization Inference
Rules Querying (with a new partial fact) What
in my database makes my fact true? What is
known about my fact?
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Bon Voyage

• Summary
• 1st passdeduction (simple)
• 2nd passfuzzy
• 3rd Bayesian belief network
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