Molecular combing

1
Molecular combing
Combing by dipping and removing
Combing by droplet drying
2
Deletions detected with molecular combing
Deletions in one of the alleles of Tuberous
Sclerosis gene (TSC2) X.Michalet et al.,
Science 277, 1518 (1997)
3
Duplication detected w. molecular combing
S.Gad et al., Oncogene 21, 6841 (2002)
4
Study of replication by molecular combing
First 60 min. replication with biot-dUTP afterward
s biot-dUTP and dig-dUTP
K.Marheineke et al., Nuc. Acid Res. 33, 6931
(2005)
5
Mapping by molecular combing
C.Conti and A.Bensimon, Genomics 80, 135 (2002)