Computational Biology Sequence Alignment

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Computational BiologySequence Alignment
Instructor Prof. Jesús A. Izaguirre Textbook
Introduction to Computational Molecular
BiologySetubal and Meidanis, Chapter
3 References Jignesh M. Patel, University of
Michigan Z. Luthey-Schulten, Bioinformatics,
NSF Summer School 2003, http//www.ks.uiuc.edu/Tra
ining http//www.dkfz-heidelberg.de/tbi/bioinfo/Pr
acticalSection/AliApplet/index.html
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Motivation

• Study sequence-sequence alignment
• Local alignment Smith-Waterman algorithm
• Global alignment Needleman-Wunsch algorithm
• Based on dynamic programming

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