Oklahoma Integrated Biotechnology Initiative IBI

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Oklahoma Integrated Biotechnology Initiative (IBI)

• EPSCoR Presentations
• Edgar ORear
• March 23, 2007

Institutions OU, OSU, UCO, OCCC
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Biotechnology

• Highlighted in EDGE Task Force Report
• Officially designated area for manpower needs by
  Federal State governments
• Growth of Presbyterian Health Foundation Research
  Park
• Oklahoma SBIRs have quadrupled with help of the
  emerging biotechnology industry

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Biotechnology OU, OSU, UCO

• No fewer than 14 hires in biotechnology over the
  last 6-7 years
• Startup funding established individual faculty
  labs
• Payoff with grants from NSF, NIH, AHA, DoD, NASA,
  OCAST includes 4 CAREER-type awardees
• How to move to the next level?

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Integrated Biotechnology Initiative
Progression of Knowledge
Knowledge
Discovery
Utilization
Engineering
Production
Integration essential for biotechnology
Tools Major research equipment attracts
researchers enables competitiveness People
Technical support improves efficiency Ideas
Shared techniques foster recognition of shared
ideas promotes collaborative research
Scientists, engineers and employees all
think about utility, direct hypothesis-driven
research and use sophisticated lab equipment
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Infrastructure Tools, Ideas, People (Incomplete
Wish List)

• Live cell imaging
• (spinng disc confocal)
• Laser tweezers
• Microfabrication,RPS
• Lithography
• Micro-CT
• Fluorescence Cell Sorter
• Bioreactors-Scaleup

• Staffed Facilities
• Industrial internships at PHRF
• Lab training OCCC technicians
• UG summer research
• Administrative support
• Research scientists

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IBI--Robust Research Facilities

• Biosensors
• Molecular Imaging
• Tissue Engineering
• Bioprocess Engineering
• Microfabrication
• Neuroscience

• Microbial Bioreactors
• Mechanotransduction
• Cell Signaling
• Physiology
• Endocrinology
• Genomics

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Bioengineering Activities in Oklahoma
Microbial/ Mammalian Cell Bioreactors
Nanotube Biosensors
Cell/Tissue Biosensors
?
Neural Sensors
Inhalation Biosensors
Protein engineering
Nanostructured Materials Microfabrication
OUBC
OUHSC
Drug Delivery
OU-Norman
Biosensors
OUBC
Sol-Gel Biosensors
Applied Biotechnology
Cell/Tissue Characteri- zation Labs
OSU
Applications Labs
OSU
Sensor Center
OUHSC
Mechanotransduction Biomechanics
Ear Bone Mechanics
Bone constructs
OSU
OUHSC /OMRF
Basic Research in Biology
Tissue engineering
Selectin-Bond Mechanics
OUBC
Platelet adhesion
Transport
Tissue Engineered Blood Vessel Mechanics
Ear Bone Mechanics
Tissue Engineering Scaffolds
Leukocyte Membrane Mechanics
Tissue Engineered Bone Mechanics

Tissue Engineered Bladders