The excitation and contraction of skeletal muscle

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CELL PHYSIOLOGY
SECTION I The Basic Organization and Functions
of Cell Membrane
SECTION II The Excitability and Bioelectric
Phenomena of Cell
SECTION III The Excitation and Contraction of
Skeletal Muscle
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The Basic Organization and Functions of Cell
Membrane
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Transport across cell membrane
Passive transport
1. Simple diffusion
The process of which a substance (lipid-soluble
particles) spreads from a region of its higher
concentration to where it is less concentrated
2. Facilitated diffusion
The protein(carrier)-assisted, non energized
transport across a cell membrane of a
substance(water-soluble particles) that is moved
along its concentration gradient.
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1. Carrier mediated diffusion
1) specificity
2) saturation
3) competitive inhibition
2. Channel mediated diffusion
1) high velocity
2)open or close
3) specificity
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3) Mechanically gated ion channel
1) Voltage gated ion channel
2) Chemically gated ion channel
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3. Active transport
The process of moving a material across a cell
membrane against its concentration gradient using
energy.
1) Primary active transport
Directly use the energy obtained from the
hydrolysis of ATP to transport material against
an energy (concentration, electrical) gradient.
2) Secondary active transport
Use the energy stored in the Na concentration
gradient to transport material against an energy
gradient.
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4. Exocytosis and endocytosis
1) exocytosis
Extracellular material is trapped within vesicles
that are formed by the invagination of the cell
membrane
2) endocytosis
Intracellular material is trapped within vesicles
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The excitation and contraction of skeletal muscle

• 1. Neuromusclar transmission
• 2. Excitation-contraction coupling
• 3.the summation of muscle fiber contraction and
  mechanics of muscle contraction

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Characteristics of neuromuscular transmission 1.
One way conduction 2. Synaptic delay 3.
Susceptibility physical chemical
factors(action of drugs etc.)
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