The Genetic Code

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The Genetic Code Transcription
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Overview of the gene expression
Klug, Cummings Spencer, 2006
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The Genetic Code
The general features of the genetic code
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Early studies The triplet nature of the Code
1960s Brenner argued on theoretical grounds
code must be a triplet since three-letter words
represent the minimal use of four letters to
specify 20 amino acids
Experimental work of Crick, Barnett, Brenner
Watts-Tobin proof for the triplet nature of the
code See p 308
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Early studies Nonoverlapping nature of the Code
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Early studies Commaless and degenarate nature
of the Code
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Studies that led to the deciphering of the code
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Decoding the Genetic Code
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Decoding the Genetic Code
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Decoding the Genetic Code
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Different initiation points
GAAAUGUAUGCAUGCCAAAGGAGGCAUCUAAGGA
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