UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE

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UCSF CLINICAL AND TRANSLATIONAL SCIENCE
INSTITUTE
February 9, 2007
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Clinical and Translational Science Institute
Aimed at providing infrastructure and support
for clinical and translational research
Designed to accommodate and to facilitate needs
of all individuals/units, in all four
schools

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Goals/mission

• Goal 1 To integrate and to enhance existing
  training programs
• Goal 2 To integrate and to enhance existing
  infrastructure required for design and
  implementation of clinical investigation and
  translational research
• Goal 3 To facilitate the career advancement of
  clinical investigators and translational
  researchers
• Goal 4 To create a home for clinical
  investigators and translational researchers,

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Initial Organization

• Overall Integrated Approach
• McCune
• Tracking Evaluation Brindis

Program Directors Team
Mike McCune Deborah Grady Joel Palefsky Dan
Lowenstein

• Informatics Segal/Showstack
• Design, Biostat, Ethics
• Johnston/Bacchetti/Lo
• Translational Methods
• Johnston
• Research Training
• Hulley/Martin/Yamamoto
• Career Advancement
• Damsky/Brown

• Pilot Studies
• Giacomini/Volberding
• Virtual Home
• Butter/Schmidt
• Community Engagement
• Grumbach/Selby
• Health Policy
• Luft/Kahn

• Regulatory Support
• Lee/Wiener-Kronish
• Participant Interaction
• Schambelan/Wara
• Translational Tech
• Nelson/Derynck/
• Waldman/Sinclair
• Global Health
• McKerrow/Padian

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Reaching the Goals
Research Implementation
Career Advancement
Research Design
Training

• Research education training
• Training in other program functions

• Design, biostatistics, ethics
• Translational methodologies

• Participant interactions
• Translational technologies
• Regulatory
• Informatics
• Community
• Global health
• Policy

• Career advancement
• Pilot studies

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Bringing the Parts Together a Virtual Home
Research Implementation
Career Advancement
Research Design
Training

• Research education training
• Training in other program functions

• Design, biostatistics, ethics
• Translational methodologies

• Participant interactions
• Translational technologies
• Regulatory
• Informatics
• Community
• Global health
• Policy

• Career advancement
• Pilot studies

CREATION OF A VIRTUAL HOME Central
Administration Web-based home Collaborative AV
Environments
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Translational ResearchCreating an Environment
for Success

• PRIORITIES
• UCSF School of Medicine Leadership Retreat
• Meritage Resort at Napa
• January 19-20, 2007

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SOM Leadership Retreat Attendance

• gt150 attendees
• Campus Leadership
• Chancellor and Vice-Chancellors
• Deans of the other UCSF Schools
• SOM Leadership
• Dean and Vice-Deans
• Chairs of Departments and Directors of ORUs and
  Programs
• Translational Researchers
• Co-directors of CTSI components
• Faculty who perform translational research
• Community Collaborators
• From CTSI affiliates

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SOM Leadership Retreat Planning

• Deans office
• Donna Ferriero, Vice Dean for Academic Affairs
• Dina Gould Halme, Director of Science Policy
• CTSI Leadership
• Mike McCune
• Deborah Grady
• Daniel Lowenstein
• Joel Palefsky
• Leaders of other Translational Researcher
  Entities at UCSF
• Jeffrey Bluestone, Immune Tolerance Network (ITN)
• Shaun Coughlin, Cardiovascular Research Institute
  (CVRI)
• Frank McCormick, Comprehensive Cancer Center
  (CCC)
• Regis Kelly, QB3

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Priorities Going Forward

• Faculty Advancement
• Support meritorious junior faculty sufficiently
  to succeed
• Develop consistent promotions guidelines/practices
  
• Revise current promotions guidelines to better
  address value of multidisciplinary team efforts

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Priorities Going Forward

• Training
• Coordinate existing graduate and professional
  programs
• Additional training in translational research,
  both for clinical and basic researchers
• Improve interaction and coordination of basic,
  translational and clinical research training

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Priorities Going Forward

• Infrastructure
• Fix regulatory issues
• Enhance scientific cores
• Improve web-based communications and knowledge
  management
• Enhance interactions with Industry
• Enhance community input to and interaction with
  UCSF research activities

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Priorities Going Forward

• Faculty Advancement (Aim 3 of CTSI)
• Training (Aim 1 of CTSI)
• Infrastructure (Aims 2 and 4 of CTSI)

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Metrics and collaboration

• Metrics to be determined on a program by program
  basis
• Collaboration Among all 4 UCSF schools and with
  national consortia