Recent Research Stories Silent Version - PowerPoint PPT Presentation

1 / 42
About This Presentation
Title:

Recent Research Stories Silent Version

Description:

Professor, Univ of Oregon, School of Medicine. Assist. Professor, Harvard Medical School ... Irvine, School of Medicine. Assist. Professor, University of ... – PowerPoint PPT presentation

Number of Views:55
Avg rating:3.0/5.0
Slides: 43
Provided by: charles146
Category:

less

Transcript and Presenter's Notes

Title: Recent Research Stories Silent Version


1
Recent Research Stories (Silent Version)
2
Recent Research Stories (Silent Version)
For sound, please feel free to come see me.

Cheers,
Geoff
3
Previous Graduates from the Rosenfeld Laboratory
Susan Amara Rouping Chen Bryan Crenshaw Daniel
Drolet Glen Evans Xi He Ola Hermanson Jeff
Holloway Holly Ingraham Kristen Jepsen
Michael Kapiloff Chrissa Kioussi
Peng Li Steve Lipkin Sergio Lira
Professor, Vollum Institute, Investigator,
HHMI Staff Scientist, Celera Genomics Assoc.
Professor, University of Pennsylvania Assoc.
Research Director, NeXagen Inc. Professor, Univ
of Texas, Southwestern, School of Medicine Asst.
Professor, Harvard Medical School Assist.
Professor, Karolinska Institute, Stockholm,
Sweden Staff Scientist, Unigen Pharmaceuticals
Inc. Professor, UC San Francisco Assoc.
Research Scientist, UC San Diego Assist.
Professor, Univ of Oregon, School of
Medicine Assist. Professor, Oregon State
University Professor, The Singapore Institute of
Biology Assist. Professor, UC Irvine, School of
Medicine Adjunct Professor, Mt. Sinai School of
Medicine
3
4
Previous Graduates from the Rosenfeld
Laboratory(continued)
Assoc. Research Scientist, UC San Diego Assoc.
Professor, Univ of Oregon, School of
Medicine Assist. Professor, Harvard Medical
School Assist. Professor, University of
Massachusetts Assoc. Project Scientist, UC San
Francisco Assist. Project Scientist, UC San
Diego Assist. Professor, Stanford
University Postdoctoral Fellow, University of
Washington Project Scientist, Illumina Professor
, UC Irvine, School of Medicine Assist.
Professor, University of Massachusetts
Robert McEvilly Geoffrey Murdoch
Anders Näär Franco Rodrigo Marcus
Schonneman Kathleen Scully Mark Sornson
Daniel Szeto Jo Yeakley Marion
Waterman Lan Xu
4
5
5
6
Biochemical Identification of the Nuclear
Receptor Corepressor (N-CoR)
6
7
LXXLL Motifs in Coactivator Function
7
8
Identification of the Minimal Corepressor/NR
Interaction Motif
8
9
Biological Roles of N-CoR (Proliferation/Transform
ation)
9
10
N-CoR is Required for NSC Maintenance and
Proliferation
10
11
N-CoR is Required to Maintain the Neural Stem
Cell State
11
12
Hypothalamic Pituitary Axis
12
13
13
14
14
15
Transient Signaling Gradients and
InducedTranscription Factors in Pituitary
Development
15
16
Heritable Defects in Mouse Pituitary Development
16
17
Pit-1 Determines Three Anterior Pituitary Cell
Types
17
18
Phenotype Variation in Prop-1 Disease Alleles
18
19
DNA Binding-independent Functions of Pit-1
Restrict Gonadotrope Gene Expression Out of
Thyrotropes
19
20
Three Pit-1 Cell Types Express
DistinctHormone-encoding Gene Targets
20
21
Co-crystal Structure of Pit-1 POU Domainson GH
and Prl DNA Response Elements
21
22
Combinatorial Recruitment of a Corepressor
Complex inLong-term Active Repression of the GH
Gene
22
23
Drosophila sine oculis Mutations
Zipursky et al. Neuron Vol. 12, 977-996 1994
23
24
Six6-/- Retinal ProgenitorCells Has Reduced
Proliferation Potential
24
25
Six6/Dach2 are Required forPrecise Regulation of
RPC Proliferation
25
26
Phenotype of Six1-/- Mice
26
27
Phenotype of Six1-/- Mice
27
28
The Eya Family are Functional Protein Phosphatases
28
29
Model of Eya Phosphatase Actions inSix1/Dach/Eya
Regulation of Organogenesis
29
30
Pitx2 / RIEG / Otlx2 / ARP1
30
31
Phenotype of Pitx2 Gene-deleted Mice
Visceral and Axial Turning Abnormalities
lung
Right Pulmonary Isomerism
Organ Determination and Proliferation
31
32
32
33
IL-1b-dependent Export of N-CoR/TAB2/HDAC3
33
34
IL-1-dependent KAI1 Gene Induction Based on a
Corepressor/Coactivator Exchange
34
35
Models of KAI1 Activation by Inflammation and
Disease
35
36
Secretase-dependent Cleavage of APP
36
37
APP Interactions with Potential Signalling
Molecules
37
38
Presenilin-dependent Generation
ofTranscriptional Coactivators
38
39
Potential REST-Regulated Gene Targets
39
40
CoREST-dependent Silencing of the rCh39q21-36
Interval
40
41
Model of CoREST-dependent Silencingof a
Chromosomal Interval
41
42
THE ENDRecent Research
StoriesbyGeoff Rosenfeld
Write a Comment
User Comments (0)
About PowerShow.com