PANCREAS

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CHAPTER 19

• PANCREAS

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PANCREAS

• Normal
• Pathology

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PATHOLOGY

• CONGENITAL
• PANCREATITIS
• CYSTS
• NEOPLASMS

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CONGENITAL

• Agenesis
• Pancreas Divisum
• Annular Pancreas
• Ectopic Pancreas

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AGENESIS
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PANCREAS DIVISUM
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ANNULAR PANCREAS
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ECTOPICPANCREAS
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PANCREATITIS

• Acute
• Chronic

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ACUTE

• Cationic Trypsinogen (PRSS1)
• Serine Protease Inhibitor, Kazal Type 1 (SPINK1)

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CHRONIC

• Pathogenesis
• Morphology
• Clinical Features

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CYSTS (NON-Neoplastic)

• Congenital
• PSEUDO-Cysts

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TUMORS

• CYSTIC
• CARCINOMA
• PANCREATOBLASTOMA

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CYSTIC TUMORS
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(ADENO) CARCINOMA

• Precursors
• Molecular
• K-RAS
• P16
• SMAD4
• P53
• Other Genes
• Methylation Abnormalities
• Gene Expression

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(ADENO) CARCINOMA

• Epidemiology
• Etiology
• Pathogenesis
• Morphology
• Clinical Features

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PANCREATOBLASTOMA