Neisseria gonorrhoeae

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Neisseria gonorrhoeae

• Case Study 2
• Group 4

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Neisseria gonorrhoeaeimages from neisseria.org
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Characteristics
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Gram Negative Diplococcus
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Can be Found Inside of WBCs
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• Incubation 2 to 5 days
• Attaches to urethral or vaginal columnar
  epithelial cells by pili and other surface
  proteins
• Portal of entry is mucous membranes of genitalia
• Causes PID ( pelvic inflammatory disease )

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Resistance

• Used to be cured 100 with Penicillin
• Developed a resistance
• Plasmid-mediated resistance
• Chromosomally resistant

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DNA Transfer images found _at_ www.bois.niu.edu

• Transmits with pili
• Has adhesins on its fimbrae
• Only adhere to cells lining urethra vagina in
  humans

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Treatment image found www.bmb.leeds.ac.uk

• Ceftriaxone
• 3rd / 4th Cephalosporin
• 1.0 gm IV

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Prognosis

• Neisseria gonorrhoeae
• Pelvic Inflammatory Disease

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Special Precautions

• Must wear PPG ( gloves, lab coat, safety glasses
  )
• All contaminated areas cleaned with antibacterial
  detergent ( must kill gram negative cocci )
• All sex partners must be notified