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Qunfeng Dong

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Qunfeng Dong. I received B.S. in Biochemistry from Wuhan University (China) in 1993. Then at Iowa State University (ISU), after I obtained my Biochemistry Ph.D. ... – PowerPoint PPT presentation

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Title: Qunfeng Dong


1
Qunfeng Dong
  • I received B.S. in Biochemistry from Wuhan
    University (China) in 1993. Then at Iowa State
    University (ISU), after I obtained my
    Biochemistry Ph.D. (molecular and cell biology)
    in 2000 and briefly spent Post-doc training (NMR
    protein structure calculation) in 2001, I had
    been working as a staff scientist leading major
    NSF-funded plant genome databases development at
    ISU. Over the years at ISU, I managed to learn
    bioinformatics by taking classes, reading papers,
    but most importantly by doing research and
    collaborating with many other bright brains.
  • In Oct 2006, I left ISU and joined the Center for
    Genomics and Bioinformatics (CGB) as
    Bioinformatics Director (a non-tenure-track
    faculty position) at Indiana University.

2
Research Area of Interest
  • Comparative genomics - Identify and understand
    functional units in genomes (what are they, where
    are they, what do they do, how were they
    evolved).
  • Cyberinfrastructure - Develop databases and
    analysis tools to facilitate comparative genome
    research, gene-expression analysis, and etc.
  • Collaboration - Data analysis (sequence and
    expression) for OTHER biologists. If I dont know
    how to do it myself (or within expertise of the
    CGB), I approach computer scientists and
    statisticians by defining the biological
    challenges as CS. or Stat. problems for clear
    communications.

3
Methods Used
  • Databases (e.g., MySQL).
  • General sequence and molecular phylogeny analysis
    tools (e.g., BLAST, CAP3, PAML). Usually I write
    a lot of Perl scripts.
  • Statistical tools (e.g., R)

4
Most significant contribution
  • PlantGDB (www.plantgdb.org)
  • Dong, Q., Wilkerson, M.D. Brendel, V. (2007)
    Tracembler - software for in-silico chromosome
    walking in unassembled genomes. BMC
    Bioinformatics, Sumitted January 15, 2007.
  • Schlueter, S.D., Wilkerson, M.D., Dong, Q.
    Brendel, V. (2006) xGDB open-source
    computational infrastructure for the integrated
    evaluation and analysis of genome features.
    Genome Biol. 7, R111.
  • Dong, Q., Lawrence, C.J., Schlueter, S.D.,
    Wilkerson, M.D., Kurtz, S., Lushbough, C.
    Brendel, V. (2005) Comparative plant genomics
    resources at PlantGDB. Plant Physiol. 139,
    610-618.
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