Chemistry 501 Handout 10 Lipids Chapter 10

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Chemistry 501 Handout 10 LipidsChapter 10
Lehninger. Principles of Biochemistry. by Nelson
and Cox, 5th Edition W.H. Freeman and Company
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Two conventions for naming fatty acids.
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Fatty Acids
Stearic acid
Oleic acid
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The packing of fatty acids into stable aggregates
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Glycerol and a triacylglycerol
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Triacylglycerols provide stored energy and
insulation
Fatty stores in cells
Guinea pig adipocytes
Cotyledon cell from a seed of Arabidopsis
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Many foods contain triacylglycerols
Fatty acid composition of three food fats
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Waxes serve as energy stores and water repellents
Triacontanoylpalmitate
The major component of beeswax
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Some common types of storage and membrane lipids
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Glycerophospholipids
The backbone of phospholipids
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Some phospholipids have ether-linked fatty acids
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Galactolipids and sulfolipids
Three glycolipids of chloroplast membranes
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Archaebacteria contain unique membrane lipids
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Sphingolipids are derivatives of sphingosine
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Sphingolipids at cell surfaces are sites of
biological recognition
Glycosphingolipids as determinants of blood groups
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Phospholipids and sphingolipids are degraded in
lysosomes
The specificities of phospholipases
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Inherited human diseases resulting from abnormal
accumulations of membrane lipids
Abnormal ganglioside deposits in lysosomes
(brain cell) Tay-Sachs
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Sterols have four fused carbon rings
Cholesterol
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Arachidonic acid and some eicosanoid derivatives
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Steroids derived from cholesterol
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Vitamin D3 production and metabolism
a hormone that regulates Ca2 uptake in the
intestines and calcium levels in kidney and bones
Rickets
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Gene SLC24A5 Two variants Difference just one
amino acid
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Vitamin A1 and its precursor and derivatives
Isoprene structural unit
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Some other biologically active isoprenoid
compounds
involved in the formation of active prothrombin
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inhibits the formation of active prothrombin
Wisconsin Alumni Research Foundation arin
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Lipids as pigments in plants and bird feathers
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Working with Lipids
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Determination of the structure of a fatty acid by
mass spectrometry