RHABDOVIRIDAE - PowerPoint PPT Presentation

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RHABDOVIRIDAE

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Describe rabies pathogenesis in mammals, including bats ... HOST RANGE: All mammals are susceptible including bats. RABIES. CONTROL: ... – PowerPoint PPT presentation

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Title: RHABDOVIRIDAE


1
RHABDOVIRIDAE
  • PETER H. RUSSELL, BVSc, PhD, FRCPath, MRCVS
  • Department of Pathology and Infectious Diseases,
    The Royal Veterinary College,
  • Royal College Street,
  • London NW1 OTU.
  • E-mail Web site

2
LEARNING OBJECTIVESStudents should be able to
  • Describe rabies pathogenesis in mammals,
    including bats
  • Relate rabies epidemiology in different countries
    to the control measures used.
  • Name the four requirements in the rabies control
    strategy recently introduced as an alternative to
    quarantine in the UK.

3
FAMILY CHARACTERISTICS
  • (Rhabdo rod )

4
RABIES
  • DISEASE PATHOGENESIS
  • Notifiable zoonotic rare in UK but several
    cases have been veterinarians!

5
RABIES
  • DISEASE PATHOGENESIS
  • Non-fatal infections are rare but skunks and
    foxes may recover dogs can have mild symptoms,
    recover and remain as excretors. Recovered
    animals have antibodies. These infections are
    important in spreading the virus in the
    environment.

6
RABIES
  • ANTIGENICITY only one type required in vaccine

7
RABIES
  • HOST RANGE All mammals are susceptible
    including bats

8
RABIES
  • CONTROL
  • The strategy depends on whether rabies is endemic
    or whether the country is free of virus.
  • Virus-free countries

9
RABIES
  • CONTROL
  • Virus endemic countries

10
RABIES
  • CONTROL
  • In humans

11
Summary
  • Rabies targets the nervous system and brain
    causing a fatal infection transmitted by biting
    as virus in saliva zoonotic.
  • Rabies-free countries aim to keep rabies out by
    quarantine countries with endemic rabies in
    wildlife control rabies by reducing wildlife
    numbers /- vaccination of wildlife.
  • In the UK, the Pet Travel Scheme has been
    introduced to replace quarantine but for
    movements between specified countries only.
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