Bury Down Unwanted Pregnancy with Abortion Pills

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Overview of Abortion Pills

• Abortion Pill is the dosage form which contains
  two active hormones, which are responsible to
  terminate the pregnancy (but the pregnancy should
  not be exceeding to 69 days).
• Misoprostol belongs to the category of medicine
  termed as synthetic prostaglandin and is act by
  causing the softening of cervix and also alters
  the lining of uterus.
• The maximum effect for terminating the pregnancy
  is successfully achieved, when Misoprostol is
  administered after the dose of Mifepristone.

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Composition of Abortion Pills

• Each pack of abortion pill contains 5 tablets,
  i.e.
• One tablet of Mifepristone (200 mg)
• Four tablets of Misoprostol (each tablet
  containing 200 mcg dose)

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How Abortion Pills Work

• Each pack of abortion pill contains two different
  hormones tablet, and then mechanism of action of
  these hormones is simultaneously different from
  each other.
• Mifepristone It has an anti progesterone
  activity, which act by binding to the
  progesterone receptors. It also possesses weak
  anti androgenic as well as weak anti
  glucocorticoid activity. It acts in various
  steps
• Inhibits the release of progesterone
• Uterine lining begins to shed
• Softening of cervix
• Bleeding occurs

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How Abortion Pills Work(Contd.)

• Misoprostol It belongs to the synthetic
  prostaglandin class, which act by binding to the
  specific receptor present on the myometrial
  cells. Thus, it acts in various steps
• Myometrial contractions
• Softening of cervix
• Contraction of uterus
• Expulsion of the uterine contents

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Contraindications of Abortion Pills

• Abortion pill effectively terminates the
  pregnancy, but in some conditions the medication
  should not be recommended to the patients.
• These conditions are
• Allergic to any ingredient of Abortion pills
• It is not effective to terminate the ectopic
  pregnancy or if any birth control device is
  placed, i.e. IUD.
• Suffered from severe adrenal or hepatic disorder
• Long term use of anticoagulant therapy
• Suffered from hemorrhagic disorders.

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Drug Interactions

• An abortion pill show its effectiveness, but its
  efficiency is reduces when some other medication
  is also taken along with the abortion pill. This
  is cause due to the interaction causes within the
  any ingredient of abortion pill and other
  medicine, which alters the therapeutic effect of
  each dosage form.
• These drugs are
• Anti coagulant drugs
• Oral Steroidal drugs
• Anti fungal drugs
• Antacids
• Anticonvulsants drugs
• Antibiotics

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Precautions of Abortion Pill

• Patients suffered from HIV should not take this
  medication.
• The dosage form should not be recommended to
  heavy smoker and alcoholic patients.
• Should not take the medication if the patient is
  not sure about her pregnancy. Because, the dosage
  form may be harmful to non pregnant lady.
• Remove the contraceptive devices before taking
  the medication, i.e. IUD.
• The dosage form of abortion pill should not be
  recommended to breast feeding mother. 

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Dose of Abortion Pills

• One tablet of Mifepristone 200 mg is taken via
  oral route, i.e. mouth, with a full glass of
  water, followed 1 to 3 days later by Misoprostol
  800 mcg (4 tablets of 200 mcg) should be
  administered vaginally.
• It is beneficial to take the medication after
  the evening time.
• Then, check the pregnancy after 14 days of
  administration of Misoprostol dose of the
  medication.
•  Surgical method for the termination of pregnancy
  is should be carried out, if the abortion pill
  fails to terminate the pregnancy.

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Side Effects of Abortion Pills
 

• After drug administration, the patient may
  experience some unwanted physical as well as
  psychological effects, along with the therapeutic
  effect.
• Vaginal bleeding is the main side effect, which
  is occurring after the administration of the
  dosage form.
• Other possible side effects are
• Nausea
• Diarrhea
• Vomiting
• Dizziness
• Headache
• Back pain
• Tiredness

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