U'S' Department of Energys Office of Science

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U.S. Department
of Energys
Office of Science
Funding Opportunities (and resources) for
Bioengineering Research at the Department of
Energy

• Office of Biological and Environmental Research

David G. Thomassen
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Department of Energy Science
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DOE constructs, operates and plans scientific
facilities for the future of science

• Leadership in High-End Computation
• Provide more than 250 teraflops capability for
  modeling and simulation of scientific
  grand-challenge problems in combustion, fusion,
  and complex chemical reactions
• 100 teraflops Blue Gene P computer to expand
  architectural diversity in leadership computing
  and address scientific challenges in materials
  science, catalysis, protein/DNA complexes, and
  advanced designs of nuclear reactors
• Increase capacity at National Energy Research
  Scientific Computing Center (NERSC) to 100-150
  teraflops for high performance production
  computing.
• Linac Coherent Light Source construction
  continues this X-Ray Free Electron Laser will
  allow examination of chemical reactions in
  real-time at the single molecule level.
  Operations to begin in 2009.
• Spallation Neutron Source (SNS) begins operations
  as the worlds forefront neutron scattering
  facility by an order of magnitude

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DOE User Facilities Continued

• DOE Nanocenters, 4 of 5 facilities begin
  operations, as the flagships of nanoscience
  providing the U.S. with resources unmatched
  anywhere in the world
• Synchrotron Light Sources, for biomolecule and
  materials structure determination. NSLS II to
  begin RD and project engineering design (PED) in
  FY 2007 a light source user facility with the
  world's finest capabilities for x-ray imaging
• Production Genomics Facility, world leading high
  throughput DNA sequencing of DOE relevant
  organisms

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Nanotechnology -- Nanoscale Science Research
Centers (NSRC)

• NSRCs are highly collaborative,
  multidisciplinary research centers and user
  facilities for the fabrication and study of
  materials at the nanoscale.
• 4 of 5 NSRCs will be operating in FY 2007
• The Molecular Foundry at LBNL (19.2M)
• The Center for Integrated Nanotechnologies at
  SNL/LANL (19.2M)
• The Center for Nanophase Materials Sciences at
  ORNL (19.2M)
• The Center for Nanoscale Materials at ANL
  (19.2M)
• Construction continues in FY 2007 at
• The Center for Functional Materials at BNL
  (18.9M)

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Nanoscale Science Research Centers Unique
Resources, Unique Capabilities
Center for Functional Nanomaterials
Unique Resource - National Synchrotron Light
Source Scientific Focus - Nanoscale strongly
correlated oxides - Charge transfer on the
nanoscale - Nanometer-thick organic films -
Nanoscale magnetism - Nanostructured
catalysts - Nanomaterials applications
Brookhaven National Laboratory
Center for Nanophase Materials Sciences
Unique Resource - Spallation Neutron Source -
High Flux Isotope Reactor Scientific Focus -
Neutron scattering to probe materials at the
nanoscale, at interfaces, and in complex
nanophase materials - Synthesis and
nanofabrication - Nanomaterials Theory
Institute - Hybrid soft/hard materials -
Organic/inorganic nano-interfaces
Oak Ridge National Laboratory
January 2006
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Genomics GTL A Vision of Systems Biology
Research

• In 10-15 years we would like to be able to start
  with a microbe or microbial community of interest
  and in a matter of days or weeks
• Generate an annotated DNA sequence
• Produce proteins and molecular tags for most/all
  proteins
• Identify the majority of multi protein complexes
• Generate a working regulatory network model
• Identify the biochemical capabilities
• Design reengineering or control strategies in
  silico

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http//genomicsgtl.energy.gov/
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General Information on the Office of Science

• http//www.sc.doe.gov/
• Program websites
• Research highlights

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Getting a Grant from the Office of Science

• http//www.sc.doe.gov/grants/grants.html
• Solicitations (current and past)
• Instructions
• Forms
• Rules, regulations, etc.

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For more information

• David G. Thomassen, Ph.D.
• Chief Scientist
• Office of Biological Environmental Research
• SC-23 / Germantown Building
• Office of Science, U.S. Department of Energy
• 1000 Independence Avenue, SW
• Washington, DC 20585-1290
• Phone [phone]
• Email david.thomassen_at_science.doe.gov
• Fax [phone]