PHA10010 PotterPharms Introduction

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PotterPharms PLC Good Health Makes Happy
Potters
Dr Tony Curtis Lennard-Jones Laboratories, Keele
University
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PotterPharms PLC Receivers or Re-launch?
Dr Tony Curtis Lennard-Jones Laboratories, Keele
University
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PotterPharms PLC

• An established, major employer in the Potteries
• International reputation for blockbuster drugs
• Many divisions are located within the region
• Each division has a specialist product portfolio

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PotterPharms PLC The Major Divisions CHE-10002
Basic Organic Chemistry

• Audley Avirex
• Burslem Biotix
• Cobridge Cholestix
• Dresden Diagnostix
• Etruria Enterex
• Fenton Farmaco
• Hanley Histaminex

• Longton Lipidex
• Milton Medico
• Shelton Statinex
• Stoke Synetica
• Tunstall Tincturex
• Ubberley Urinex

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PotterPharms PLC The Minor Divisions CHE-10026
Basic Organic Chemistry for the Life Sciences

• Basford Botanica
• Clayton Clinica
• Endon Emetix

• Meir Metapharms
• Porthill Pyranex
• Trentham Technico

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PotterPharms PLC Brownfield Sites PHA-10010
Pharmaceutical Chemistry

• Holditch Hormones
• Madeley Macrolides
• Norton Nitrates
• Parkhouse Pyretics
• Silverdale Statins
• Sneyd Steroids

• Bentilee Barbiturates
• Chell Cytotoxics
• Diglake Diuretics
• Florence Formulations
• Foxfield Fluorides

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Pilgrim Pharmaceuticals
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Pilgrim Pharmaceuticals

• Anthony Avirex
• Cremyll Cholestix
• Devonport Diagnostix
• Freathy Farmaco
• Ham Histaminex

• Leigham Lipidex
• Mutley Medico
• Saltash Synetica
• Torpoint Tincturex

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PotterPharms PLC

• Several key PotterPharms patents have expired
• The core market is flooded with generic drugs and
  profits are the lowest for many years
• A new blockbuster drug must be introduced ahead
  of schedule to keep the company afloat

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PotterPharms PLC

• The PotterPharms board will give a contract to
  only one division to produce the blockbuster drug
• Each division must bid for the contract
• The division must have a high quality, high
  impact campaign and a product with good margins
• Staff in the successful division will be rewarded
• Staff in other divisions face an uncertain future

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PotterPharms PLC

• The employees of each division are hired from the
  local pool of students at Keele
• Employees are assigned to divisions based upon
  their discipline and personality type
• All employees are hired to be team players
• Team members must contribute to all tasks

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PotterPharms PLC

• Review the synthesis for 1 kg of the blockbuster
• Conduct a thorough risk assessment
• Design a suitable laboratory in existing space
• Devise a PR strategy to convince neighbours
• Produce a marketing leaflet and poster
• Keep a complete account of all finances
• Produce a company portfolio and poster

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PotterPharms PLC

• PotterPharms task is carried out in teams
• Each team contains 4 or 5 members
• Students are allocated to a team based upon the
  results of a Belbin-style questionnaire
• Each team operates as an autonomous unit and is
  responsible for arranging meetings, etc
• Groups are given advice on successful teamwork

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PotterPharms PLC

• Get to know all members of your team
• Fix meeting times in advance and stick to them
• Have team rules!
• Set an agenda or objective for each meeting
• If necessary, choose a leader and recorder
• Delegate tasks for each team member
• Set deadlines and stick to them
• Resolve all issues as soon as they arise

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PotterPharms PLC

• Assessment is by poster and portfolio only
• Deadlines are set to ensure sufficient time for
  formative feedback at each stage
• Posters are solely peer assessed
• Portfolios are assessed by The Chair
• Student effort is totally self/peer assessed
• Student effort mark is used to moderate
  individual student marks

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PotterPharms PLC Where Did It All Go Wrong?

• Chemistry/Medicinal Chemistry CHE-10002
• 2003-2004 33 students responded
• 2004-2005 38 students responded
• 2005-2006 54 students responded
• 2006-2007 50 students responded
• Biomedical Sciences CHE-10026
• 2004-2005 27 students responded
• 2005-2006 39 students responded
• 2006-2007 25 students responded
• Pharmacy PHA-10010
• 2006-2007 44 students responded

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PotterPharms PLC Where Did It All Go Wrong?
I thought it was a valuable experience to work on
an exercise as part of a team
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PotterPharms PLC Where Did It All Go Wrong?
I prefer this style of team-based exercise to
traditional scripted problems
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PotterPharms PLC Where Did It All Go Wrong?
I learned a lot by taking part in this exercise
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PotterPharms PLC Where Did It All Go Wrong?
I learned a lot about each aspect.because I had
an input to every task
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PotterPharms PLC Where Did It All Go Wrong?
More time was needed to complete each activity
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PotterPharms PLC Where Did It All Go Wrong?
Feedback should be given at every stage of the
exercise
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PotterPharms PLC Where Did It All Go Wrong?
More feedback was needed at each stage
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PotterPharms PLC Where Did It All Go Wrong?
More supporting material for this exercise should
be incorporated in the module
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PotterPharms PLC Where Did It All Go Wrong?
Teams shouldinclude a mixture of students from
CHE-10002 and CHE-10026
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PotterPharms PLC Where Did It All Go Wrong?
I would recommend that similar exercises be
introduced into other modules
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PotterPharms PLC Staff Unrest
In general, the exercise was a success. I was
put in a group of people who I wouldn't usually
work with, so it was good to work with people who
I didn't know
More help with the project would have been
useful because its something I haven't done
before so more help on what was needed to be done
would have been appreciated
The whole project seemed rather vague - nobody
seemed to know what they were doing at any point
of the exercise! More explanation and feedback
needed
In theory this is an excellent way to learn and
practice teamwork. The possibilities for learning
how to use the different software on computers
today is endless as well. However, if you're
rubbish at computers and not a team player, this
is not a pleasurable task .....I ultimately
enjoyed it though...
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PotterPharms PLC The Rise of the Machines

• Resources available previously on LTR server
• WebCT had potential to streamline the company
• Divisions had access to their individual
  resources
• Discussion groups enabled virtual meetings
• Deadlines were set for individual assignments
• The Chair could provide input at every stage
• Technology enabled employees to produce work for
  feedback faster than expected by The Chair
• Employees working smarter but with low morale

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PotterPharms PLC Call In The Receivers

• Logistical and practical problems that existed
  prior to 2006-2007 were ignored for one last push
• The Chair chose to expand the company mission and
  diversify further into module PHA-10010
• WebCT encouraged a 24/7 culture in employees that
  was not anticipated by The Chair
• Feedback could not be given quickly enough
• The Chair has now taken a position elsewhere
• CHE-10002, -10026 under new management

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PotterPharms PLC The Re-launch

• Diversification to include PHA-10010 spread the
  company resources too thinly to cope well
• The Chair lost sight of the company ethos/the
  plot
• PHA-10010 is now the focus for consolidation
• Employees have diverse backgrounds, wide-ranging
  skill sets and experience of teamwork
• The number of employees will certainly increase
• PotterPharms Regeneration

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For further information Dr Tony
Curtis a.d.m.curtis_at_chem.keele.ac.uk
Dr Tony Curtis Lennard-Jones Laboratories, Keele
University