NIH Partnering with Maryland Companies

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NIH Partnering withMaryland Companies

• Mark Rohrbaugh, Ph.D., J.D.
• Director
• Office of Technology Transfer
• National Institutes of Health
• U.S. Department of Health Human Services
• www.ott.nih.gov

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Opportunities

• NIH as source of trained workforce
• Licensing IP from NIH
• Collaborations with NIH to address industrys
  scientific challenges
• Access to expertise and facilities
• University-NIH-industry

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NIH Scientist-Entrepreneur

• Sherrie Bale GeneDx
• Martha Knight CC Biotech
• Bruce Weintraub Trophogen
• Frank Robey AriaVax

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Entrepreneurial Education Programs
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NIH Licensees
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NIH Licensed Products
AcuTect? AIDS Test Kit Alfaxan injectable
anaesthetic for cats/dogs Apodasi? (ddI)
Beaucage Reagent BIOMAX Multi-Blot Kit BRCA1
Diagnostic Certiva? CHAPS Gardasil Generic
ddI delayed-release capsules Fludara Fecolator
Havrix ImmunoWELL Kepivance? KLEPTOSE
(betacyclodextrin) Matrigel Invasion Chamber
Mirakelle? NeoTect? NeuTrexin
OcuvitePreserVision? ParaSight F? Parvovirus
B19 enzyme immunoassay PathVysion? Prezista
HER-2 DNA Probe Kit PixCell? Soluble
Interleukin-2 Receptor SPORANOX oral solution
Squirrel Free? capsaicin-treated birdseed
Synagis? Taxol TAXUS? coronary stent system
Thyrogen? TWINRIX TransProbe-1 Velcade?
Videx Vitravene? ZENAPAX ZEVALIN?
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Pipeline to PartnershipsNeglected DiseasesRare
Diseases
MARKETING INITIATIVES
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Collaborating with NIH Scientists

• Material Transfer Agreements
• Clinical Trial Agreements
• CRADAs

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Selected Products Developed under NIH CRADAs
original technology from University of Michigan
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NIH Conflict of Interest Rules 2005

• No outside consulting with biotech and pharma
  companies
• Official duties not affected including scientific
  collaborations with no personal compensation

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NIH CRADAs

• Total active in FY08 347
• With MD companies 18 (5.2)
• FY05 FY06 FY07 FY08
• New 80 51 44 72

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Enhancing NIH-Biotech Collaboration

• Informal
• Biotech attendance at public NIH scientific
  presentations
• NIH scientist presentations to companies
• Facilitating access to local incubators
• Communication of COI rules
• Identification of perceived and real logjams
• Formal
• Partnering for scientific personnel exchanges
• TEDCO MOU and Showcase

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Transforming medicine through discovery
NIH