Bacterial expression System in Creative BioMart (1)

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Bacterial expression System in Creative BioMart
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• Over the years, Creative BioMart has developed
  BacTECTM and FoldEZTM technologies to tackle
  hard-to-express and hard-to-dissolve proteins.
  With BacTECTM technology, the protein expression
  level can be greatly improved for almost all of
  the proteins. In addition, over 98 of the
  inclusion bodies can be refolded and solubilized
  by our proprietary FoldEZTM protein refolding
  technology.

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Slide Title

• Typically, the first choice for the expression of
  recombinant proteins is E. coli. Protein product
  in E. coli expression is fast, convinent,
  well-established and usually high yields.
• Newly-built facilities supporting a vast array of
  state-of-the-art equipment are leveraged by our
  experienced PhD-level scientists to deliver
  proteins expressed via microbial systems quickly
  and economically.

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• One of the most popular technologies is BacTECTM
  system. Creative BioMart's patented BacTECTM
  system is capable of achieving high levels of
  soluble expression proteins. While the technology
  has shown it can express many types of proteins,
  it has established a track record for producing
  high-quality, correctly folded antibody fragments
  (including Fabs and scFv).

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• Our BacTECTM protein refolding technology is
  designed to determine the optimal refolding
  conditions by evaluation a series of buffers. We
  provide refolded protein at purity of 95 or
  greater.
• Exclusively from Creative BioMart, OxiCytoTM
  competent E. coli strains are engineered to
  enable the folding of recombinantly expressed
  proteins in vivo. The expression of the
  isomerase, DsbC, within the OxiCyto cytoplasm
  enhances the correct formation of disulfide bonds
  in proteins that require them for biological
  activity.

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• Our Bacillus subtilis system is an ideal option
  for the expression of monomeric protein products
  at high expression levels. This high yield,
  combined with our patented fermentation protocols
  allow for fast process development and scale-up
  to support early clinical testing.

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Contact Creative BioMart

• Address 45-1 Ramsey Road Shirley, NY 11967, USA
• Email contact_at_creative-biomart.com
• Website http//www.creativebiomart.net