Cabometyx 20mg Tablets | Cabozantinib | MHP

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Cabometyx 20mg tablet-MillionHealthPharmaCABOZANT
INIB 20MG
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DESCRIPTION
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DESCRIPTION

• Cabometyx 20mg is a prescription medicine
  required to treat people with medullary thyroid
  cancer (MTC) which has spread to other parts of
  the body known as metastatic MTC.
• Cabometyx 20mg is highly protein bound and there
  is a hypothetical risk that it will displace
  combination withwarfarin, so INR monitoring is
  recommended.
• Cabometyx 20mg is not known if using in
  childrensafe and effective.

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INDICATION

• Cabometyx 20mg is Indicated for following
  conditions
• The treatment of Metastatic medullary thyroid
  cancer 
• The treatment of Advanced renal cell carcinoma
  (RCC) who have getting before anti-angiogenic
  therapy.
• The treatment of Hepatocellular cancer who have
  previously received sorafenib. 

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MECHANISM OF ACTION

• Cabozantinib is also known as targeted therapy
  whichaims and attach to the tyrosine kinase
  receptors and prohibits the activity of multiple
  tyrosine kinases, contains RET, MET, and VEGF on
  the surface of the cell.
• By connecting to these receptors, Cabozantinib
  stops important pathways whichdevelop cell
  division. 

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PROPERTIES

• Ingredients Cabozantinib
• Strength 20mg 
• Package 30 tablets 

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ADME

• Maximum plasma concentration is observed in 2-5
  hours
• Human serum protein bounding of Cabometyx is
  99.7
• Mostly metabolized by CYP3A4 and minorly by
  CYP2C9.
• The drug excreted mostly via feces 54 and in
  urine 27 and half-life is 55 hours.

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DOSAGE MANAGEMENT

• Do not substitute Cabometyx tablets with
  Cabozantinib capsules.
• The prescribed dose of Cabometyx is 60 mg. 
• Administration Cabometyx is without food. 
• Tell the patients dont not havefood for at least
  2 hours before and 1 hour after taking cabometyx.
• Continue the treatment until patient no longer
  experiences clinical benefit or experiences
  unacceptable toxicity.
• Swallow Cabometyx tablets whole. Do not crush
  Cabometyx tablets. 

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PRECAUTIONS

• Interrupt the Cabometyx 20mg tablet  in patients
  who develop an acute myocardial infarction,
  cerebral infarction, or any other clinically
  significant arterial thromboembolic
  complication. 
• Interrupt the Cabometyx 20mg for patient if have
  severe hypertension that cannot be controlled
  with anti-hypertensive therapy.

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• Checkthe patients for symptoms of perforations
  and fistulas, included abscess.
  discontinueCabometyx 20mg in patients who
  experience a perforation or a fistula.
• Avoid administration Cabometyx 20mg to patients
  with a present history of patients with
  haemorrhage or haemoptysis.
• Advice pregnant women aboutpossible risk to a
  foetus. Hence inform females of reproductive
  possible to use effective contraception during
  treatment with Cabometyx 20mg tablet  and for 4
  months after the last dose. 

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 SIDE EFFECTS

• The following side effects ofcabometyx 20mg
• GI perforations and fistulas
• Thrombotic events
• Hypertension and hypertensive crisis
• Diarrhea
• Palmar-plantar erythrodysesthesia

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SIDE EFFECTS

• Haemorrhage
• Reversible posterior leukoencephalopathy syndrome
• Weight loss
• Decreased appetite
• Nausea

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• Fatigue
• Oral pain
• Neutropenia
• Low platelets
• Taste changes
• Hair colour changes
• High blood pressure

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• Low potassium
• Hair loss
• Dizziness
• Joint pain
• Swallowing trouble
• Muscle spasms
• Dyspepsia (indigestion)
• Skin redness
• Reduced sodium 

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• PREGNANCY
• Pregnancy Category is D Based on studies of
  animal and mechanism of action, Cabometyx 20mg
  will cause risk to fetus when given to pregnant
  women.
• Avoid pregnancy while on treatment with Cabometyx
  20mg tablet .
• LACTATION
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• Advise the women not to breastfed to infants
  while on treatment with Cabometyx 20mg drugs
  because of possible risk to the fetus.
• STORAGE
• Store the drug at 20C to 25C
• Keep away from the children resistances

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CONTACT US

• PHONE NO91-9940472902 
• EMAILmillionhealthpharmaceuticals_at_gmail.com 
• WEBSITEhttps//millionpharma.com/cabozantinib-20m
  g.php

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