Title: Meningitis B Vaccine in Sheffield
1Meningitis B Vaccine in Sheffield
enquiries_at_regentstreetclinic.co.uk
www.regentstreetclinic.co.uk
44114358 3930
2Whats the big deal?
The charity Meningitis UK, estimates that there
are 1,870 cases of meningitis B each year in the
UK. Meningitis B is most common in children under
five years old, and in particular in babies under
the age of one. This disease kills around 1 in 10
of those affected and a significant proportion of
survivers are left with life-affecting problems.
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3What is this vaccine for?
It has been developed to give protection against
meningococcal group B disease, the most common
type of bacterial meningitis and septicaemia in
the UK. There are other types of meningitis that
will not be prevented by this vaccine. It is
vital that everyone knows the signs and symptoms
of meningitis and septicaemia, and gets urgent
medical help if they are concerned.
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4How effective would this vaccine be and does it
cover all strains?
This vaccine is the first one to demonstrate
potential coverage of (protection against) the
majority of MenB strains. However, the vaccine
will not protect against all cases of MenB, but
coverage estimates show that 73 of Men B
infection will be covered.
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5Why doesnt it cover all strains?
There are many different Men B strains. This
vaccine has been developed to offer protection
against as many as possible. Once it has been in
use for some time, it will be possible to
calculate the coverage and continue with vaccine
research to improve the protection it gives.
Knowing the signs and symptoms and seeking early
medical help remain vital in saving lives.
Clinical trials have shown that this vaccine (as
do all vaccines) stimulates the bodys immune
system to generate protective antibodies.
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6Does the vaccine have any known side-effects?
In infants and children (less than 2 years of
age) the most common adverse reactions observed
in clinical trials were tenderness and swelling
at the injection site, fever and irritability.
Taking paracetamol or similar painkillers at the
time of vaccination or shortly afterwards can
help reduce the risk of such reactions. Remember
painkillers should only be taken as instructed.
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7How effective are the meningitis vaccines that
are currently in use?
Over the past 20 years, vaccines that prevent
different types of meningitis have been
introduced into the childhood immunisation
schedule and also given to others at increased
risk. These vaccines have prevented thousands of
cases saving lives and significantly reducing
the number of people living with life-long
disabilities.
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8Why has it taken so long to develop a vaccine for
Men B?
Most vaccines are made from part of the outer
coating of a bacterial cell. The outer coating of
the meningococcal B strain is very complex, so
the usual methods of producing a vaccine have not
been successful. Many years of research have been
undertaken to develop new ways of producing a
vaccine. Bexsero is licensed for individuals
from 2 months of age and older. Clinical data
support the use of Bexsero within the current UK
schedule at 2, 3, 4 and 12 months.
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9Were any unusual side effects seen in the trials?
Like all vaccines, this vaccine can cause side
effects although not everybody gets
them. Uncommon side effects, described as up to
1 in 100 people, are high fever, seizures
(including febrile seizures), vomiting (after
booster) dry skin, itchy rash, skin rash,
paleness (rare after booster). Rare side effects
(may affect up to 1 in 1,000 people), Kawasaki
syndrome (a rare condition that mainly affects
children under the age of five. It is also known
as mucocutaneous lymph node syndrome).
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10CONTACT US
ADDRESS
Kingfisher House 90 Rockingham St Sheffield S1
4EB United Kingdom Phone 44 114 358 3930
Email enquiries_at_regentstreetclinic.co.uk
www.regentstreetclinic.co.uk
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