Karyotyping

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Karyotyping
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What is a karyotype?

• An standard arrangement of an organisms
  chromosomes during metaphase of mitosis.

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What is the purpose of using a karyotype?

• Karyotypes allow us to view the entire organisms
  complement of chromosomes.
• This allows doctors to diagnose different genetic
  disorders during the gestation period of the
  organism

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Karyptype Analysis

• To write an organisms Karyotype Analysis
• Write the TOTAL number of chromosomes
• Write the sex chromosomes that are seen
• Males will have one X and one Y chromosome
• Females will have TWO X chromosomes
• Record any abnormalities
• Deletions, duplications, translocations

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Normal Male

• 46, XY

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Normal Female

• 46, XX

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NONDISJUNCTION

• Failure of chromosomes to separate properly
  during anaphase

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Female with Down Syndrome

• 47, XX, 21