%identity with a protein of known structure - PowerPoint PPT Presentation

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%identity with a protein of known structure

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Protein fold recognition by prediction-based threading 'TOPITS'. Rost, Schneider, Sander ... Fold Recognition (Threading) University of Ghent, 2000. Alfonso ... – PowerPoint PPT presentation

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Title: %identity with a protein of known structure


1
3D Structure prediction
Ab initio
Threading
Homology modeling
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30
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identity with a protein of known structure
2
Rost, Schneider, Sander (1997) J. Mol. Biol.
270, 471-480
3
Threadlize
Interactive inspection and manipulation of
threading models http//gredos.cnb.uam.es
Pazos, Rost, Valencia 1999
4
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5
Plotcorr
http//gredos.cnb.uam.es
Pazos, Olmea Valencia, 1997
6
Sequence features related to structure and
function
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CASP2 (1997) Fold Recognition (Threading)
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CASP3 (1999). Threading.
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CASP4 (2000) our predicitons
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- Threading prog. Score - Cons. Res. Closeness. -
Tree-det " - Corr. Mut " - Apolar res. " - Fold
compactness - Fold predicted by diff. Threaders.
Threading model
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Threading server methods
13
CAFASP2 (2000)Servers for Automatic Structure
Predictions
14
http//gredos.cnb.uam.es
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