DISCONTOOLS

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DISCONTOOLS

• Gap Analysis.
• Brussels
• 31March 2009
• Jim Scudamore

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ETP Global Animal HealthThe Vision July 2005

• To facilitate and accelerate the development and
  distribution of the most effective tools for
  controlling animal diseases of major importance
  to Europe and the rest of the world, thereby
  improving human and animal health, food safety
  and quality, animal welfare, and market access,
  contributing to achieving the Millennium
  Development Goals.

Published August 2005
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ETP Global Animal HealthThe Strategic Research
Agenda May 2006

• The SRA is the mechanism to deliver the vision.
• SRA has 2 overarching objectives-
• to deliver new and improved tools for the control
  of major diseases and
• to deliver the recommendations in the SRA which
  in turn will facilitate the development and
  delivery of new tools

Published May 2006
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ETP Global Animal HealthSRA Theme 2 Gap analysis

• Issues are considered under 5 headings-
• Gaps Disease Knowledge
• Gaps Product Availability re vaccines,
  diagnostic tests and pharmaceuticals
• Gaps Sourcing of Products
• Gaps Technology Usage
• Gaps Research Activity
• 8 recommendations to conduct gap analysis

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ETP Global Animal Health Action Plan First
Stages

• The first stage is to identify and prioritise the
  diseases of importance. The second stage is to
  assess the gaps in the knowledge and
  understanding of these diseases to identify where
  research needs to be targeted. At the same time
  the gaps in the availability of products will be
  evaluated.
• With the implementation of the recommendations
  from these two themes it will be possible to
  select priority diseases and identify the
  research needed to fill the gaps in knowledge
  along with the actions needed to develop new and
  improved tools for control of those diseases.

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Discontools

• WP1 Project Management and Coordination
• WP2 Disease Prioritisation
• WP3 Gap analysis
• WP4 Technology Evaluation
• WP5 Communication and dissemination

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Revised prioritisation model following the WP2
meeting in October 2008 and chairs meeting
February 09

• Disease knowledge
• Impact on wider society
• Impact on public health
• Impact on international trade
• Control Measures
• Collection of information

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Theme 1 Model discussed at meeting 10 March
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Theme 1 Update on prioritisation following
meeting on 10 march
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Gap analysis

• Methodology
• What type of information?
• Who will collect information?
• Where from?
• How will the information be collated?
• Where will it be stored?
• Who will evaluate and analysed?
• How will information be disseminated?
• Who will disseminate?

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Gap analysis
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Gap analysis

• Methodology
• What type of information?
• Who will collect information?
• Where from?
• How will the information be collated?
• Where will it be stored?
• Who will evaluate and analysed?
• How will information be disseminated?
• Who will disseminate?

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Disease and Gap analysisInitial information
sheet.

• Product/Gap Analysis
• Commercial Diagnostics available
• Commercial Diagnostics available in Europe
• Diagnostics in Ref Labs 
• DIVA test
• Effectiveness
• Commercial Vaccine availability (globally)
• Vaccine authorised in Europe
• Marker Vaccines available
• Marker vaccine in Europe
• Live or dead
• Application
• Recombinant/GM VaccinesEffectiveness
• Commercial potential of vaccines in Europe
• DIVA tests
• Current Therapy
• Future therapy
• Requirements for product development
• Requirements for diagnostic tests

• Disease analysis
• Description of disease
• Geographical distribution
• Species affected
• Transmission
• Immunology
• Main means of prevention and control
• Zoonotic potential
• Disease outbreaks reported to OIE in last 18
  months
• Economic impact
• Main perceived obstacles for effective prevention
  and control
• Main perceived facilitator for effective
  prevention and control

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Information sheet.

• Example
• African Swine Fever.

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Disease and Product AnalysisDisease
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DISCONTOOLS

• Tasks
• Identify and agree the relevant criteria for gap
  analysis
• Develop a peer reviewed methodology for gap
  analysis
• Electronic collection of information for the gap
  analysis of each of the priority diseases in a
  standard format using the same system as for the
  disease prioritisation information.
• The results of the gap analysis will need to be
  subjected to peer review in order to have
  agreement on the priorities for targeting
  research funding. Peer review the information
  gathered
• Identify the gaps in knowledge for each of the
  diseases.
• Produce a disease summary for each priority
  disease listing the gaps and identifying research
  required to develop new and improved methods of
  control especially in relation to specific
  control measures such as surveillance, treatment,
  vaccines and diagnostic tests.
• As with prioritisation, the majority of this work
  will be developed through expert/working groups,
  stakeholders, seminars and workshops as
  appropriate. Other work will be conducted in
  house.

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DISCONTOOLS

• Deliverables
• A validated methodology for gap analysis (month
  18)
• Answers to specific question re tools for disease
  control (month 24)
• What is currently available for effective
  controls and is it fit for purpose?
• What new tools are needed?
• Is the research near to a breakthrough and does
  it have the potential to deliver the products?
• What are the costs and timescales for delivery of
  the new tools?
• A comprehensive standardised analysis for each of
  the priority diseases identifying the gaps in
  knowledge and availability of control tools
  (month 36)
• A comprehensive database with web access for each
  of the priority diseases (month 42)
• Final report on research requirements to fill the
  gaps and encourage the development of new or
  improved tools for each of the priority diseases.
  (month 48)
• Final report of a standardised validated
  methodology to determine gaps and research
  priorities with more accuracy. (month 48)