Anti-Anginal Agents

1
Anti-Anginal Agents

• Angina
• Disease, symptoms
• Types of Anti-anginal Agents
• Nitrovasodilators, calcium channel blockers and
  b-blockers
• Nitrovasodilators
• Structure, physical properties, biochemical
  mechanism of action, metabolism and
  pharmacokinetics
• Calcium channel blockers
• Types, structure, physical properties,
  biochemical mechanism of action

2
Angina
3
Nitrovasodilators
4
Structure
Nitrate Esters
5
Pharmacokinetics of Nitrate Esters
6
Biochemical Mechanism of Action
7
Calcium channel blockers
8
Structure of Ca2 channel blockers
9
Protein Binding of Calcium Channels Blockers