PTP%20Domain

1
Identification of SHP3 a pseudogene with
apparent exon structure on chromosome 1p36.32
PTP Domain
SH2
SH2
Exon 1A
2
3
5
4
8
6
7
9
10
11
12
13
14
15
5 UTR
SHP1 Gene
(201)
3 UTR
1B
123
195
190
117
97
92
114
80
150
132
155
68
152
(111)
5 UTR
11 400 bp 60 GC
53 Identity (Amino Acid)
65
68
59
51
60
61
61
62
49
68
66
69
43
54
SHP2 Gene
3 UTR
5 UTR
70
123
195
193
117
97
113
114
80
132
155
68
152
159
gt 80 000 bp 42 GC
?
?
45 Identity (Amino Acid)
65
44
58
52
57
64
54
54
45
65
64
51
?
SHP3 Pseudogene
8 300 bp 65 GC
123
195
196
99
97
112
83
170
68
127
132
155
http//ptp.cshl.edu or http//science.novonordisk.
com/ptp
Andersen et al (FASEB J) 2003