FP5 and FP6 projects of interest to 2FUN

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• FP5 and FP6 projects of interest to 2-FUN
• Tuomo Karjalainen
• March 2007

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FP5 projects

• List of projects and final reports available
• http//ec.europa.eu/research/ quality-of-life/ka4/
  index_en.html

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• European Environment and Health Action Plan
  adopted in 2004? 38 projects funded by the Sixth
  Framework of Research (2002-2006) with a total EC
  contribution of 205M ? first results becoming
  available

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Research supporting Actions 1-4
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Research supporting Action 5 Integrate and
strengthen European environment and health
research
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Research supporting Action 6 Target research on
diseases, disorders and exposures
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Research supporting Action 6 Target research on
diseases, disorders and exposures
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Research supporting Action 6 Target research on
diseases, disorders and exposures
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Research supporting Action 6 Target research on
diseases, disorders and exposures
DIEPHY
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Research supporting Action 7
Develop methodological systems to
analyse interactions between environment and
health
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Research supporting Action 7
Develop methodological systems to
analyse interactions between environment and
health
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Research supporting Action 7
Develop methodological systems to
analyse interactions between environment and
health
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Research supporting Action 7
Develop methodological systems to
analyse interactions between environment and
health
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Research supporting Action 8 Ensure that
potential hazards on environment and health are
identified and addressed
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Research supporting Action 8 Ensure that
potential hazards on environment and health are
identified and addressed
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Research supporting Action 8 Ensure that
potential hazards on environment and health are
identified and addressed
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Research supporting Action 9 Develop public
health activities and networking on environmental
healthdeterminants through the public health
programme
Not applicable for RTD
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Research supporting Action 10 Promote training
of professionals and improve organisational
capacityin environment and health
Not applicable for RTD. However, many integrated
projects and Networks of Excellence have
extensive training programmes in EH
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Research supporting Action 11 Co-ordinate
ongoing risk reduction measures on the priority
diseases
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Research supporting Action 12 Improve indoor air
quality
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Websites
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Selected publications
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IA methodological developments

• Health and environment
• NOMIRACLE (IP, 2005) http//nomiracle.jrc.it
• INTARESE (IP, 2006) http//www.intarese.org
• HEIMTSA (IP, 2007)
• ESPREME/DROPS (2003/2006)
• ENVIRISK (2007)

• Environmental sciences
• EUSAAR (IP, 2006) www.eusaar.net
• ACCENT (NoE, 2005) www.accent-network.org
• COST 633 http//cost633.dmu.dk

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INTARESE Integrated Assessment of Health Risks
of Environmental Stressors in Europe

• The aim
• To develop, test and apply a methodology for
  integrated assessment of health risks from
  environmental stressors, in order to support
  policy in the EU
• The challenge
• Dealing with complexity
• Dealing with uncertainty
• Lack of monitoring data
• Research and knowledge gaps
• Lack of consistent and effective tools and
  methods
• Inadequate or poorly specified indicators

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INTARESE Sub-projects and WPs
SP7. Co-ordination and management
SP 6 User consultation and dissemination
6.1 User concerns and information needs 6.2
Dissemination
SP 3 Policy assessments
SP1 Integrated assessment methods
3.1 Transport 3.2 Housing 3.3 Agricultural land
use 3.4 Water 3.5 Chemicals in household products
and articles 3.6 Waste 3.7 Climate
1.1 Assessment framework 1.2 Source-exposure 1.3
Exposure-effect 1.4 Risk characterisation 1.5
Cross-cutting issues
SP 5. Integration and training
5.1 Integration 5.2 Training
SP 4 Integrated assessment system
SP 2 Monitoring and surveillance
2.1 Environmental monitoring 2.2
Biomonitoring 2.3 Health surveillance 2.4
Integrated monitoring
4.1 Toolbox design 4.2 Toolbox development 4.3
Application and testing
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Inception phase
Framework development
Develop assessment methodology
Refinement of methods
Reporting
Support to SP3
SP1
Request for methods
Assessment methods/ protocols
Revised assessment methodology
Feedback on assessment methods
Assessment framework
Review of data/models etc
Scoping
1st assessment
2nd assessment
SP3
Feedback on data
Request for data
Data delivery
Enhanced data
Results from SPs 1-3
Support to SP3
Reporting
SP2
Review of sources and construction of inventory
Development and testing of new methods
System construction
Scoping
System design
SP4
Application/case studies
Reporting
SP5
User needs WS
Methods WS
1st assessment WS
System demo WS
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HEIMTSA

• HEIMTSA
• HEALTH and
• ENVIRONMENT
• INTEGRATED
• METHODOLOGY and
• TOOLBOX for
• SCENARIO
• ASSESSMENT
• An Integrated Project under FP6 - 5M Commission
  Funding

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HEIMTSA Broad aims

• Quantify as fully as practicable the
  environmental health effects of policies in
  various sectors
• Policies designed to improve health
• Health effects of policies developed for other
  reasons
• Give a fair unbiased assessment of
• Uncertainties in what is included
• What is omitted
• Identify priority information/knowledge gaps
• Priority having a major influence on answers
• Enable assessment of environmental health effects
  of future policies

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HEIMTSA Schematic diagram
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HEIMTSA Broad aims of stream 3

• Identify risk relationships from existing
  epidemiological studies for quantifying
  pollutant-health pathways
• Concentration-response (C-R) functions (e.g.
  classical air pollutants based on fixed point
  monitored concentrations)
• Exposure-response (E-R) functions (e.g. for
  indoor air, based on measured or modelled
  individual exposures)
• Dose-response (D-R) functions (e.g. for the
  effect on childrens IQ of lead in blood based on
  dose modelled through biological monitoring)
• Integrate across exposures by various routes
  (inhalation, dermal, ingestion) to derive
  biological markers for which D-R functions can
  be developed
• Develop methods for estimating effects of
  mixtures
• Estimate background rates of the relevant health
  effects

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The ENVIRISK project

• Aims at developing methodologies for exposure
  assessment and health risk assessment that would
  be transferable to the European level
• Bases itself on two major EH databases CZ and SK

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CZ PM2.5 and PAH (IEM Prague)
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Risk of IUGR and PM10 (IEM Prague)
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INTERPRETATION OF MOLECULAR EPIDEMIOLOGY RESULTS
NEW KNOWLEDGE ABOUT POLLUTANTS AFFECTING HUMAN
HEALTH
RISK ASSESSMENT
R. J. Sram 2007
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SOURCE PCBRISK project, prof. Tomas Trnovec
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PCBRISK PCB Concentrations in Ambient Air
Michalovce (polluted district) vs Stropkov
(control district)
Turany n/O.
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Lomné
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Stropkov District
Brusnica
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Potocky
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Stropkov II
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Stropkov I
200
Strazske
Vola
Michalovce II
280
Michalovce District
Michalovce I
100
Hazin
110
Senne
110
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PCB Concentration pg/m

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HENVINET in summary

• EU-funded Coordination Action
• start 1.11.2006, runs for 42 months
• 30 partners from 17 countries (5 outside Europe)
• Coordinator Inga Fløisand, NILU
• Support development of integrated health and
  environment policies
• Environment and Health Action Plan
• Environment and Health Information System
• Focus on four priority health diseases asthma
  and allergies, cancer, neurodevelopmental
  disorders, endocrine disruptors

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HENVINET objectives (2)

• Perform initial reviews
• Develop plans for validation studies and actively
  work towards the wider use of decision support
  tools
• Thus identify possible emerging issues regarding
  health and environment relations
• Identify relevant ongoing and recently completed
  research projects focused on DSTs
• Review the information in a systematic way
• Exploit the DSTs compatible with the EHAP and
  identify linkages of existing tools to enhance
  them
• Identify gaps of knowledge and suggest validation
  studies

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structure
information
WP 1Evaluation and exploitation of best
practices WP 4Validation and exploitation of
decision support tools
WP 2System and database
WP 3Interaction with policy and dissemination
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