Immunization and planning for influenza outbreaks

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Influenza Vaccination in 56 Countries, 1997-2003
MIV SG 2005
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• Reported (BOE)
• 20,000-50,000 cases / yr
• lt 10 deaths / yr
• Estimated (IEIP MOPH)
• Flu pneumonia gt 900,000 OPD visits / yr
  nationwide
• Flu as the cause in 10 of hospitalized
  pneumonia
• Higher severity and mortality in high risk groups
  (eg. COPD, heart disease, asthma, etc.)

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• Costs
• Medical cost for treatment of flu and related
  illnesses
• Opportunity costs / loss of production
• Intangible costs
• Cost-benefit of flu vaccination
• Cost-saving from flu vaccination

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Path towards influenza pandemic
10 Sep 06
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15 Aug 08
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15 Aug 08
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?????????????/????? (Non-med/non-pharma)
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systems - to keep the society running)
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Source David Nabarro at APEC-HMM, Sydney 8 June
2007
15 Aug 08
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10
Non-Pharmaceutical Pharmaceutical Strategies
Pandemic vaccine
15 Aug 08
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15 Aug 08
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Projected use of influenza vaccine in Thailand,
20002015 a favorable scenario
Scale up to produce pandemic vaccine
Technology Cell-culture Adjuvant LAIV
Vaccine production project Increased use of flu
vaccine Capacity building
Note 2000-2003 figures -- from Simmerman et al.
2004 -2005 figures initial projection
15 Aug 08
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Note 2000-2003 figures -- from Simmerman et al.
2004 -2005 figures initial projection
15 Aug 08
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Note 2000-2003 figures -- from Simmerman et al.
2004 -2005 figures initial projection
26 Sep 08
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